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Charcot-Marie-Tooth disease (CMT) is a neuromuscular disorder that progressively affects the peripheral nervous system. It can lead to progressive lower extremity weakness but can also affect the other organs. CMT symptoms vary from person to person, but can include weakness or numbness in the feet and legs, problems with balance and coordination, difficulty walking, and pain in affected areas. In some cases, CMT can also cause problems with bladder or bowel function, breathing, and heart rate.
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