Osmosis video - Intraoral Biopsy Techniques for Pemphigus & Pemphigoid

Intraoral biopsy techniques are used to take a small sample of tissue from inside the mouth. This type of biopsy is used to diagnose pemphigus and pemphigoid, both autoimmune diseases that cause blisters in the mouth and on the skin.

There are a few different intraoral biopsy techniques that can be used, depending on where in the mouth the biopsy is needed. A scalpel may be used to make a small cut in the tissue, or a tiny instrument called a curette may be inserted into a natural opening such as the side of the tongue. The biopsy sample is then collected and sent to a lab for analysis.