Video - Opsoclonus myoclonus syndrome (NORD)

Opsoclonus-myoclonus syndrome (OMS) is a rare condition, characterized by rapid, uncontrolled eye movements (opsoclonus) and sudden twitching or jerking of muscles (myoclonus). It can also present with ataxia, which often results in the inability to walk, sit or crawl, and the loss of previously attained abilities, like speech.

The cause of OMS is not well understood, but it is thought to be due to an autoimmune condition in which the body attacks the nervous system, resulting in characteristic signs and symptoms. Treatment involves immunosuppressive therapy like corticosteroids, intravenous immunoglobulin or IVIG, drugs like cyclophosphamide, and rituximab.