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Clonorchis sinensis

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Clonorchis sinensis

Parasitology

Ectoparasites

Pediculus humanus and Phthirus pubis (Lice)
Sarcoptes scabiei (Scabies)

Protozoa

Acanthamoeba
Naegleria fowleri (Primary amebic meningoencephalitis)
Toxoplasma gondii (Toxoplasmosis)
Cryptosporidium
Entamoeba histolytica (Amebiasis)
Giardia lamblia
Babesia
Plasmodium species (Malaria)
Leishmania
Trichomonas vaginalis
Trypanosoma brucei
Trypanosoma cruzi (Chagas disease)

Worms

Diphyllobothrium latum
Echinococcus granulosus (Hydatid disease)
Ancylostoma duodenale and Necator americanus
Angiostrongylus (Eosinophilic meningitis)
Anisakis
Ascaris lumbricoides
Enterobius vermicularis (Pinworm)
Guinea worm (Dracunculiasis)
Loa loa (Eye worm)
Onchocerca volvulus (River blindness)
Strongyloides stercoralis
Toxocara canis (Visceral larva migrans)
Trichinella spiralis
Trichuris trichiura (Whipworm)
Wuchereria bancrofti (Lymphatic filariasis)
Clonorchis sinensis
Paragonimus westermani
Schistosomes

Key Takeaways

Clonorchis Sinensis is a liver fluke that is found in East Asia and Southeast Asia. It is a human liver parasite known to cause clonorchiasis, an infection characterized by right upper quadrant abdominal pain, jaundice, fever, diarrhea, and even death. It is contracted by ingesting raw or undercooked fish. Clonorchis sinensis infection can complicate into cholangitis and cholangiocarcinoma.

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Flashcards

Clonorchis sinensis

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Questions

USMLE® Step 1 style questions USMLE

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A 41-year-old man is hospitalized for cholangitis. Two months ago he traveled around eastern Asia and ate several meals consisting of raw fish. Temperature is 38.3°C (100.9°F), blood pressure is 138/80 mmHg, and pulse is 85/min. Laboratory studies reveal an alkaline phosphatase of 415 U/L (reference range: 20-70 U/L) and total bilirubin of 4.1 mg/dL (reference range: 0.1-1.0 mg/dL). Both liver biopsy and serum tests for Echinococcus granulosus are negative. A stool sample is collected and found to contain several eggs. Which of the following pathologies is most likely responsible for this clinical presentation?