Megaloblastic anemia
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Megaloblastic anemia
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Glossitis
megaloblastic anemia p. 426
Megaloblastic anemia p. 423, 426
cytarabine p. 444
Diphyllobothrium latum p. , 157
as drug reaction p. 249
macro-ovalocytes in p. 420
orotic aciduria p. 426
trimethroprim p. 191
tropical sprue p. 388
vitamin BNaN deficiency p. 66
vitamin BNaN deficiency p. 67
Methotrexate p. 443
megaloblastic anemia p. 249
Neutrophils p. 412
megaloblastic anemia p. 426
nonmegaloblastic anemia p. 426
Phenytoin
megaloblastic anemia p. 249
Sulfa drugs p. 251
megaloblastic p. 249
Summary
Megaloblastic anemia is a type of anemia caused by deficiencies in folic acid (folate) or vitamin B12. Folic acid and vitamin B12 are essential for DNA synthesis, and thus the production of healthy red blood cells. Megaloblastic anemia is characterized by large, nucleated red blood cell precursors which don't divide and produce more red blood cells as normal precursor cells do. Symptoms include fatigue, shortness of breath, and pale skin.