Osmosis video - Alkylating agents: Nursing pharmacology

Alkylating agents are antineoplastic drugs that work by inhibiting the transcription of DNA to RN by alkylation. Alkylation is the process of adding an alkyl group ( �CH3) to DNA. This process prevents the DNA from being used in protein synthesis and the production of new cells, including cancer cells. Some common alkylating agents include cyclophosphamide, chlorambucil, and melphalan.