Osmosis video - Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
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Video Summary of Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a type of antiviral medication used to treat HIV infection. They work by inhibiting the HIV's reverse transcriptase enzyme, thus preventing the multiplication of the virus.
Some NNRTIs such as efavirenz and delavirdine are teratogenic. Non-teratogenic NNRTIs include nevirapine and etravirine. Common side effects of NNRTIs include hypersensitivity reactions, dizziness, hallucinations, vivid dreams, and in some cases, there may be toxic epidermal necrolysis and Stevens-Johnson syndrome.