Osmosis video - Polymyositis

Polymyositis is an inflammatory disorder of the muscles, caused mainly by cytotoxic T- cells destroying muscle tissue due to molecular mimicry and resulting in bilateral proximal muscle weakness of large muscle groups. It is characterized by muscle weakness, muscle pain, and difficulty with activities of daily living. Its diagnosis involves elevated serum creatinine kinase and myositis- specific antibodies, and it is treated with corticosteroids and specialized physical exercise.