Video - Type II hypersensitivity

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Video Summary

Type II hypersensitivity is a type of immune response in which the immune system attacks the body's own cells or tissues. Type II hypersensitivity is mediated by antibodies, such as IgG and IgM, directed against antigens on host cells, which cause cell and tissue destruction by complement activation or antibody-dependent cell-mediated cytotoxicity. Examples of Type II hypersensitivity reactions include blood transfusion reactions, erythroblastosis fetalis, and autoimmune hemolytic anemia. Treatment options may include avoiding the tigger, and immunosuppressive medications such as systemic glucocorticoids.