Video - Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare endocrine disorder characterized by a triad of one or more gastrinomas, increased gastric acid secretion, and peptic ulcers. The main symptom is epigastric pain from peptic ulcers, but also includes steatorrhea, weight loss, gastrointestinal bleeding, and diarrhea due to incomplete digestion and absorption. Zollinger-Ellison syndrome can be treated with acid-lowering medications and surgery to remove solitary tumors. Treatment involves reducing the production of stomach acid with medications, removing the tumor through surgery.