Bartholin Cyst

Bartholin Cyst: What Is It, Causes, Signs and Symptoms, and More

Author: Nikol Natalia Armata
Editor: Alyssa Haag
Editor: Ian Mannarino, MD
Illustrator: Jillian Dunbar
Copyeditor: David G. Walker
Editor: Anna Hernández, MD
Modified: Oct 15, 2024

What is a Bartholin cyst?

A Bartholin cyst refers to the enlargement of one of the Bartholin glands located on either side of the vaginal opening. The Bartholin glands, also known as the greater vestibular glands, are a pair of small excreting glands that produce a mucus-like fluid that acts as lubrication of the vaginal opening during sexual intercourse. When the ducts of these glands become obstructed, fluid can back up and form a Bartholin cyst, causing a palpable lump near the vaginal opening. 

Sometimes, the obstructed Bartholin duct can become infected and form an abscess, leading to pain around the vaginal opening, pain during intercourse, discomfort while walking, as well as fever. One thing to note is that abscesses are not always preceded by cysts, and they occur three times more often. 

An infographic detailing the background, causes, signs and symptoms, diagnosis, and treatment of Bartholin cysts.

What causes a Bartholin cyst?

Bartholin cysts are caused by the obstruction of one of the Bartholin glands. Blockage in the drainage of the gland leads to the accumulation of the fluid, which builds up over time, causing a cystic dilation of the gland. The reason why a Bartholin duct may become blocked is not clear, however, they are more likely to occur in sexually active individuals due to the friction caused by sexual intercourse. Additional risk factors include sexually transmitted infections, such as chlamydia or gonorrhea, urinary tract infections, and trauma to the genital area, such as during childbirth or an episiotomy performed after a vaginal delivery 

While Bartholin cysts can occur at any age, they are more common among individuals between 20 and 30 years old. Enlargement of the Bartholin gland in individuals over 40 years old should raise suspicion for malignancy, especially if the gland is fixed, firm, or shaped irregularly.  

What are signs and symptoms of a Bartholin cyst?

The presentation of a Bartholin cyst may vary depending on its size and location. Small cysts usually present as a painless, unilateral lump in the lower right or left part of the vulvar vestibule (i.e., the area between the labia minora). Swelling of the labia majora may also be evident on the affected side. Larger cysts may cause pain and discomfort, particularly when walking, sitting or having sexual intercourse. Fever, redness, and intense pain in the surrounding area are usually present in individuals with a Bartholin abscess.   

How is a Bartholin cyst diagnosed?

A Bartholin cyst is diagnosed clinically after a thorough review of symptoms, medical history, and physical examination. Most cases do not require further laboratory or imaging studies. However, when medical intervention is required, a microbial culture or biopsy of the cyst may be taken to rule out infection or malignancy, respectively. If sexually transmitted infections are suspected, STI testing (e.g., gonorrhea and chlamydia) should be performed in order to initiate appropriate treatment as soon as possible.  

How is a Bartholin cyst treated?

Treatment for a Bartholin cyst varies depending on the severity of symptoms and size of the cyst. Conservative measures, such as warm water soaks or sitz baths, can provide symptomatic relief in mild cases and are the first line of treatment in most cases.   

If the cyst is large or painful, a clinician may perform a simple drainage procedure. Drainage is typically performed by creating a small incision within the cyst to allow the collected fluid to drain. A flexible silicone tube called Word catheter may be inserted into the cyst to help prevent recurrence by keeping the cyst cavity open. The catheter is usually left in place for several days to weeks, depending on the size of the cyst and the amount of fluid being drained. 

In cases of recurrence, a marsupialization procedure may be performed by a gynecologist. This procedure involves creating a small permanent opening in the cyst wall to allow continuous drainage and prevent re-accumulation of fluid. In rare cases, if cysts are persistent and troublesome, surgical removal of the Bartholin gland may be considered. 

Pregnant individuals with Bartholin cysts should be treated in the same way as non-pregnant individuals, with the exception of Bartholin gland excision, which should be avoided due to pregnant individuals’ increased risk of bleeding.  

Because of the presence of other lubricating glands in the vaginal opening, removal of a Bartholin gland does not affect lubrication during sexual intercourse.   

In cases of Bartholin abscesses, or when an underlying infection is suspected, antibiotic treatment (e.g., clindamycin, amoxicillin-clavulanate, trimethoprim-sulfamethoxazole) may also be prescribed.  

What are the most important facts to know about Bartholin cyst?

Bartholin cysts refer to a painless dilation of a Bartholin gland that develops in individuals assigned female at birth during their reproductive age. They are mainly caused by obstruction of the gland’s duct, which can be associated with infections (e.g., STIs) or trauma. Usually, Bartholin gland cysts are asymptomatic or associated with mild symptoms, like swelling and tenderness of lower vulvar vestibule. Diagnosis occurs after a thorough review of medical history and physical examination. Medical interventions are typically required only when symptoms are significant and include drainage of the cyst, cyst marsupialization, and surgical removal of the cyst. In cases complicated by an abscess, antibiotic therapy may also be prescribed.  

References


Bati-Paracha A, Sharma M. Management of Bartholin’s cyst and abscess. Obstet Gynaecol. 2023;25(1):72-77. doi:10.1111/tog.12847  


Illingworth BJG, Stocking K, Showell M, Kirk E, Duffy JMN. Evaluation of treatments for Bartholin’s cyst or abscess: A systematic review. BJOG. 2020;127(6):671-678. doi:10.1111/1471-0528.16079 


Lee MY, Dalpiaz A, Schwamb R, Miao Y, Waltzer W, Khan A. Clinical pathology of Bartholin’s glands: A review of the literature. Curr Urol. 2015;8(1):22-25. doi:10.1159/000365683  


Omole F, Kelsey RC, Phillips K, Cunningham K. Bartholin duct cyst and gland abscess: Office management. Am Fam Physician. 2019;99(12):760-766. Accessed October 8, 2024. https://www.aafp.org/pubs/afp/issues/2019/0615/p760.pdf