Author: Anna Hernández, MD
Editor: Alyssa Haag
Editor: Emily Miao, PharmD
Editor: Kelsey LaFayette, DNP, ARNP, FNP-C
Illustrator: Jessica Reynolds, MS
Copyeditor: David G. Walker
Modified: Jan 06, 2025
What is the Brudzinski sign?
The Brudzinski sign is one of the physical maneuvers used to evaluate an individual for a suspected case of meningitis, a condition characterized by inflammation of the meninges (i.e., the protective membranes surrounding the brain and spinal cord).
A viral, bacterial, parasitic, or fungal infection typically causes meningitis. The classic triad of meningitis symptoms is nuchal rigidity (i.e., neck stiffness), fever, and headache. If meningitis is suspected, a lumbar puncture can analyze cerebrospinal fluid (CSF) and identify the underlying cause.
How is the Brudzinski sign performed?
Brudzinski sign is performed with the individual lying flat on their back. The examiner then places one hand behind the individual’s
head and the other on their chest to prevent them from rising. A positive Brudzinski sign is considered when neck flexion causes the individual to
flex their hips and knees automatically.
The Brudzinski sign is often performed with the Kernig sign. To elicit the Kernig sign, a leg is raised with the knee
flexed to a 90-degree angle. Resistance, pain, or inability to extend the knee indicates a positive Kernig sign.
What are the limitations of the Brudzinski sign?
Negative Brudzinski and Kernig signs should not rule out
meningitis. The Brudzinski and Kernig signs were described over a century ago in individuals with severe, late-stage
tuberculous and bacterial meningitis. Several studies have shown low sensitivity to Kernig and Brudzinski signs to detect meningitis. Nonetheless, because of their high
specificity, if Kernig or Brudzinski sign is present, meningitis is likely.