Granulocytosis
What Is It, Causes, Treatments, and More
What is granulocytosis?

What is the function of granulocytes?
What causes granulocytosis?
Granulocytosis may be caused by bone marrow disorders, and may also be seen in conjunction with infections and autoimmune disorders.
Most commonly, granulocytosis is caused by bone marrow disorders which cause the number of granulocytes produced in the marrow to increase. One of the most common bone marrow disorders resulting in granulocytosis is chronic myeloid leukemia, a cancer of the white blood cells. Other bone-marrow-related disorders that can result in granulocytosis include polycythemia vera (causing an increase in red blood cells), primary myelofibrosis (causing destruction of the bone marrow and consequent bone marrow scarring), and essential thrombocythemia (causing an increase in platelets).
Infections, especially those caused by bacteria, can also cause granulocytosis. Such cases result from the body’s natural immune response to fight off the infection; as more neutrophils are produced in order to attack the bacteria, granulocytosis may occur.
Finally, autoimmune disorders, such as rheumatoid arthritis may also result in granulocytosis. Individuals with rheumatoid arthritis generally have chronic inflammation of the joints which can often result in an increased amount of circulating granulocytes.