SAMPLE

Secondary Assessment Acronym

Author: Georgina Tiarks, MD
Editor: Alyssa Haag, MD
Editor: Józia McGowan, DO
Editor: Kelsey LaFayette, DNP, ARNP, FNP-C
Illustrator: Jannat Day
Modified: Jan 29, 2026

What is a secondary assessment?

The secondary assessment is a systematic evaluation that occurs in traumas or life-threatening situations to help a medical team efficiently gather pertinent information related to the patient’s condition. This happens after or in conjunction with the primary assessment, which evaluates the airway, breathing, circulation, disability, and exposure, or ABCDE. Once the patient is stabilized, the secondary assessment can be completed. The purpose is to analyze vital signs, complete a physical examination, obtain a detailed history of present illness, and gather relevant medical history. If the individual cannot participate or answer questions, then an attempt should be made to collect information from a bystander, friend, or family. Clinicians can use the SAMPLE acronym to gather this information systematically.   

In addition to asking questions, the clinician should complete a thorough physical exam, or head-to-toe assessment, to evaluate the patient’s current state and gather more information. To begin, vital signs including heart rateblood pressure, oxygen saturation, temperature, and respiratory rate should be evaluated and analyzed. Vital sign changes can indicate an underlying condition such as shock, hemorrhage, respiratory distress, or infection. The physical exam may require urgent evaluation of the presenting issue, such as the site of hemorrhage or fractured bone. Then, a head-to-toe assessment may be conducted, which includes evaluation of the head (e.g., trauma, bruising); neck, while ensuring C-spine stability (e.g., jugular venous distension); chest (e.g., crepitus, tenderness, respiratory effort, heart sounds, lung sounds, rash); abdomen (e.g., tenderness to abdominal palpation, distension, bruising); back (e.g., bruising, costovertebral angle tenderness); perineum (e.g., pelvic instability, bleeding); extremities (e.g., radial pulsesposterior tibial pulses and swelling, bruising, visible bone fracture); and neurologic system (e.g., pupil size, eye movements, facial movement, sensation, strength, reflexes). Fetal heart tones, fundal height, and bleeding should also be assessed in patients who are pregnant.  

An infographic detailing SAMPLE, the secondary assessment acronym.

What is SAMPLE?

The SAMPLE acronym is used by clinicians as a systematic way to ensure all crucial information is gathered to prevent missed information that can reduce mortality and morbidity. 

What does the “S” in SAMPLE mean?

The “S” in SAMPLE refers to the signs or symptoms the patient is experiencing. The clinician can ask questions such as, “What are you feeling?”, “Are you in pain?”, “Where is the pain?”, “When did this begin?”, “Can you describe the pain to me?”, or “Can you rate your pain on a scale of 1-10?”. The answers to these questions can give an insight into the underlying cause of the patient’s condition and management.  

What does the “A” in SAMPLE mean?

The “A” stands for allergies. Medications may need to be given to manage the patient’s condition, so it’s important to identify any allergies that may contribute to a reaction. Additionally, this can help clinicians determine if an allergic reaction or hypersensitivity contributed to the condition. Evaluation should include allergies to medications, foods, supplements, and the environment.  

What does the “M” in SAMPLE mean?

The “M” stands for medications. Medications have a variety of side effects, which could either be the cause of the condition or may interact with other medications that are given for treatment. For example, if a patient takes a blood thinner such as warfarin, they may require a reversal agent and additional imaging to ensure they don't have internal bleeding. Furthermore, if a patient sustained a fall, certain medications, like  benzodiazepines or tricyclic antidepressants, should be considered as they may have contributed to the fall.  

What does the “P” in SAMPLE mean?

The “P” refers to past medical history. This includes previous diagnoses or medical illnesses the patient has experienced, and it provides insight into the patient’s general health.  

What does the “L” in SAMPLE mean?

The “L” stands for last oral intake. This involves identifying the approximate time the patient had eaten or drank anything. This provides insight into whether the patient could be dehydrated or malnourished. This also informs surgical clinicians in the event the patient requires urgent surgery, as anesthesia can increase the risk of aspiration depending on time of last oral intake.  

What does the “E” in SAMPLE mean?

The “E” means events leading up to the trauma to provide context to the situation. The clinician may ask questions such as, “What happened before this?” or “What were you doing right before this happened?” This can help identify external factors that could have caused the condition such as handling chemicals or guns, being involved in an altercation, or being in a building with poor ventilation.   

What are the most important facts to know about the SAMPLE acronym?

The SAMPLE acronym is used to help clinicians recall the information necessary to gather during a secondary assessment. The secondary assessment is typically following a trauma or life-threatening event, and is completed after the initial assessment, once the patient has been stabilized. It includes completion of a physical exam, assessment of vital signs, and gathering other important medical information. The “S” refers to signs and symptoms; the “A” refers to allergies; “M” refers to medications the patient takes; “P” stands for past medical history; “L” refers to last drink or meal; and the “E” stands for events that preceded the event.  

Key Takeaways

Definition 

The SAMPLE acronym is used by clinicians as a systematic way to ensure all crucial information is gathered to prevent missed information that can reduce mortality and morbidity. 

Secondary Assessment 

- Systematic evaluation during traumas or life-threatening situations, after/together with primary ABCDE assessment  

- Gather information related to patient’s condition after stabilization 

- Consists of:  

     - Vital signs assessment  

     - Urgent evaluation of presenting issue  

     - Head-to-toe assessment  

S 

Signs or symptoms  

- Questions to patient on signs and symptoms experienced 

- Question examples: “What are you feeling?”, “Are you in pain?”, “Where is the pain?”, “When did this begin?”, “Can you describe the pain to me?”, or “Can you rate your pain on a scale of 1-10?” 

A 

Allergies 

- Allergies to medications, food, supplements, environment  

- Can help determine if an allergic reaction contributed to the condition  

M 

Medications 

- Could be the cause of the condition or interact with medications used to manage it  

P 

Past medical history  

L 

Last oral intake 

- Time the patient last ate/drank anything  

- Insight on dehydration or malnourishment  

- Helps determine risk of aspiration if anesthesia is needed 

E 

Events leading up to the trauma 

- Question examples: “What happened before this?” or “What were you doing right before this happened?” 

- Can help identify cause of the condition  

References


Galvagno SM Jr, Nahmias JT, Young DA. Advanced Trauma Life Support® update 2019: Management and applications for adults and special populations. Anesthesiol Clin. 2019;37(1):13-32. doi:10.1016/j.anclin.2018.09.009 


Jacquet GA, Hamade B, Diab KA, et al. The emergency department crash cart: A systematic review and suggested contents. World J Emerg Med. 2018;9(2):93-98. doi:10.5847/wjem.j.1920-8642.2018.02.002 


Jayaprakash N, Ali R, Kashyap R, Bennett C, Kogan A, Gajic O. The incorporation of focused history in checklist for early recognition and treatment of acute illness and injury. BMC Emerg Med. 2016;16(1):35. Published 2016 Aug 31. doi:10.1186/s12873-016-0099-9 


Jones C. First Aid Acronyms Explained – SAMPLE - First Aid Training Cooperative. June 27, 2022. Accessed August 25, 2024. https://firstaidtrainingcooperative.co.uk/acronyms-sample/