Cryptococcus neoformans

Summary of Cryptococcus neoformans
Cryptococcus neoformans is a heavily encapsulated yeast and an obligate aerobe. It is non-dimorphic and has narrow-based budding. It is often found in bird excrement and soil, and thus immunocompromised patients are at risk for opportunistic infection via inhalation and subsequent hematogenous spread. Its dissemination may lead to central nervous system involvement in the forms of cryptococcal meningitis and cryptococcal encephalitis.

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Cryptococcus neoformans

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High Yield Notes
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Cryptococcus neoformans

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is a dark stain is used to visualize Cryptococcus neoformans.

Questions

USMLE® Step 1 style questions USMLE

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USMLE® Step 2 style questions USMLE

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A 56-year-old Hispanic man comes to the office complaining of recurrent headaches, fever, and vision disturbances. His medical history is relevant to positive HIV. Physical exam shows a malnourished appearance, neck rigidity, and a positive Brudziński sign. A lumbar puncture is obtained and cultured. The microorganism grows in Sabouraud agar and has a microscopic appearance of an encapsulated yeast with narrow-based budding. Which of the following stains would most likely reveal the organism responsible for this patient's symptoms?

External References