Introduction to the cardiovascular system

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Introduction to the cardiovascular system

Back to the Basic Sciences

Diagnoses

Anatomy of the coronary circulation
Anatomy clinical correlates: Heart
Coronary artery disease: Pathology review
Anticoagulants: Direct factor inhibitors
Anticoagulants: Heparin
Antiplatelet medications
Thrombolytics
Renal failure: Pathology review
ACE inhibitors, ARBs and direct renin inhibitors
Anatomy of the lungs and tracheobronchial tree
Anatomy clinical correlates: Pleura and lungs
Alveolar surface tension and surfactant
Breathing cycle and regulation
Gas exchange in the lungs, blood and tissues
Pulmonary shunts
Regulation of pulmonary blood flow
Respiratory system anatomy and physiology
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Zones of pulmonary blood flow
Obstructive lung diseases: Pathology review
Anatomy of the abdominal viscera: Liver, biliary ducts and gallbladder
Anatomy clinical correlates: Other abdominal organs
Bile secretion and enterohepatic circulation
Liver anatomy and physiology
Cirrhosis: Pathology review
Anatomy of the heart
Anatomy of the coronary circulation
Anatomy of the inferior mediastinum
Anatomy of the superior mediastinum
Anatomy clinical correlates: Heart
Anatomy clinical correlates: Mediastinum
Cardiac afterload
Cardiac contractility
Cardiac cycle
Cardiac preload
Cardiac work
Cardiovascular system anatomy and physiology
Changes in pressure-volume loops
Frank-Starling relationship
Measuring cardiac output (Fick principle)
Microcirculation and Starling forces
Pressure-volume loops
Stroke volume, ejection fraction, and cardiac output
Heart failure: Pathology review
Anatomy of the coronary circulation
Anatomy clinical correlates: Heart
Cardiovascular system anatomy and physiology
Atherosclerosis and arteriosclerosis: Pathology review
Coronary artery disease: Pathology review
Anatomy of the cerebral cortex
Anatomy of the limbic system
Anatomy clinical correlates: Cerebral hemispheres
Dementia: Pathology review
Mood disorders: Pathology review
Selective serotonin reuptake inhibitors
Serotonin and norepinephrine reuptake inhibitors
Tricyclic antidepressants
Monoamine oxidase inhibitors
Atypical antidepressants
Pancreas histology
Diabetes mellitus: Pathology review
Dyslipidemias: Pathology review
Lipid-lowering medications: Fibrates
Lipid-lowering medications: Statins
Miscellaneous lipid-lowering medications
Enteric nervous system
Esophageal motility
Gastrointestinal system anatomy and physiology
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Hypertension: Pathology review
ACE inhibitors, ARBs and direct renin inhibitors
Adrenergic antagonists: Beta blockers
Calcium channel blockers
Thiazide and thiazide-like diuretics
Anatomy of the thyroid and parathyroid glands
Thyroid and parathyroid gland histology
Endocrine system anatomy and physiology
Thyroid hormones
Hyperthyroidism: Pathology review
Anatomy of the thyroid and parathyroid glands
Thyroid and parathyroid gland histology
Endocrine system anatomy and physiology
Thyroid hormones
Hypothyroidism: Pathology review
Introduction to the skeletal system
Bone remodeling and repair
Bone disorders: Pathology review
Anatomy of the abdominal viscera: Pancreas and spleen
Anatomy clinical correlates: Other abdominal organs
Pancreas histology
Pancreatic secretion
Pancreatitis: Pathology review
Anatomy of the diaphragm
Anatomy of the larynx and trachea
Anatomy of the lungs and tracheobronchial tree
Anatomy of the nose and paranasal sinuses
Anatomy of the pleura
Bones and joints of the thoracic wall
Muscles of the thoracic wall
Vessels and nerves of the thoracic wall
Anatomy clinical correlates: Pleura and lungs
Anatomy clinical correlates: Thoracic wall
Alveolar surface tension and surfactant
Anatomic and physiologic dead space
Breathing cycle and regulation
Gas exchange in the lungs, blood and tissues
Lung volumes and capacities
Pulmonary shunts
Regulation of pulmonary blood flow
Respiratory system anatomy and physiology
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Zones of pulmonary blood flow
Pneumonia: Pathology review
Drug misuse, intoxication and withdrawal: Alcohol: Pathology review
Drug misuse, intoxication and withdrawal: Hallucinogens: Pathology review
Drug misuse, intoxication and withdrawal: Other depressants: Pathology review
Drug misuse, intoxication and withdrawal: Stimulants: Pathology review
Atypical antidepressants
Nasal, oral and pharyngeal diseases: Pathology review
Anatomy of the abdominal viscera: Kidneys, ureters and suprarenal glands
Anatomy of the female urogenital triangle
Anatomy of the male urogenital triangle
Anatomy of the perineum
Anatomy of the urinary organs of the pelvis
Anatomy clinical correlates: Female pelvis and perineum
Anatomy clinical correlates: Male pelvis and perineum
Renal system anatomy and physiology
Urinary tract infections: Pathology review
Anatomy of the lungs and tracheobronchial tree
Fascia, vessels and nerves of the upper limb
Vessels and nerves of the forearm
Vessels and nerves of the gluteal region and posterior thigh
Anatomy clinical correlates: Pleura and lungs
Clot retraction and fibrinolysis
Coagulation (secondary hemostasis)
Platelet plug formation (primary hemostasis)
Deep vein thrombosis and pulmonary embolism: Pathology review
Anticoagulants: Direct factor inhibitors
Anticoagulants: Heparin
Anticoagulants: Warfarin

Clinical conditions

Abdominal quadrants, regions and planes
Anatomy of the abdominal viscera: Blood supply of the foregut, midgut and hindgut
Anatomy of the abdominal viscera: Esophagus and stomach
Anatomy of the abdominal viscera: Innervation of the abdominal viscera
Anatomy of the abdominal viscera: Large intestine
Anatomy of the abdominal viscera: Liver, biliary ducts and gallbladder
Anatomy of the abdominal viscera: Pancreas and spleen
Anatomy of the abdominal viscera: Small intestine
Anatomy of the anterolateral abdominal wall
Anatomy of the diaphragm
Anatomy of the gastrointestinal organs of the pelvis and perineum
Anatomy of the inguinal region
Anatomy of the muscles and nerves of the posterior abdominal wall
Anatomy of the peritoneum and peritoneal cavity
Anatomy of the vessels of the posterior abdominal wall
Anatomy clinical correlates: Anterior and posterior abdominal wall
Anatomy clinical correlates: Inguinal region
Anatomy clinical correlates: Other abdominal organs
Anatomy clinical correlates: Peritoneum and diaphragm
Anatomy clinical correlates: Viscera of the gastrointestinal tract
Appendicitis: Pathology review
Diverticular disease: Pathology review
Gallbladder disorders: Pathology review
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Inflammatory bowel disease: Pathology review
Pancreatitis: Pathology review
Acid-base map and compensatory mechanisms
Buffering and Henderson-Hasselbalch equation
Physiologic pH and buffers
The role of the kidney in acid-base balance
Acid-base disturbances: Pathology review
Anatomy of the abdominal viscera: Kidneys, ureters and suprarenal glands
Kidney histology
Renal system anatomy and physiology
Renal failure: Pathology review
Anatomy of the basal ganglia
Anatomy of the blood supply to the brain
Anatomy of the brainstem
Anatomy of the cerebellum
Anatomy of the cerebral cortex
Anatomy of the cranial meninges and dural venous sinuses
Anatomy of the diencephalon
Anatomy of the limbic system
Anatomy of the ventricular system
Anatomy of the white matter tracts
Anatomy clinical correlates: Anterior blood supply to the brain
Anatomy clinical correlates: Cerebellum and brainstem
Anatomy clinical correlates: Cerebral hemispheres
Anatomy clinical correlates: Posterior blood supply to the brain
Nervous system anatomy and physiology
Amnesia, dissociative disorders and delirium: Pathology review
Central nervous system infections: Pathology review
Cerebral vascular disease: Pathology review
Dementia: Pathology review
Drug misuse, intoxication and withdrawal: Alcohol: Pathology review
Drug misuse, intoxication and withdrawal: Hallucinogens: Pathology review
Drug misuse, intoxication and withdrawal: Other depressants: Pathology review
Drug misuse, intoxication and withdrawal: Stimulants: Pathology review
Mood disorders: Pathology review
Schizophrenia spectrum disorders: Pathology review
Seizures: Pathology review
Traumatic brain injury: Pathology review
Anticonvulsants and anxiolytics: Benzodiazepines
Atypical antipsychotics
Typical antipsychotics
Blood histology
Blood components
Erythropoietin
Extrinsic hemolytic normocytic anemia: Pathology review
Intrinsic hemolytic normocytic anemia: Pathology review
Macrocytic anemia: Pathology review
Microcytic anemia: Pathology review
Non-hemolytic normocytic anemia: Pathology review
Introduction to the central and peripheral nervous systems
Introduction to the muscular system
Introduction to the skeletal system
Introduction to the somatic and autonomic nervous systems
Anatomy of the ascending spinal cord pathways
Anatomy of the descending spinal cord pathways
Anatomy of the muscles and nerves of the posterior abdominal wall
Anatomy of the vertebral canal
Anatomy of the vessels of the posterior abdominal wall
Bones of the vertebral column
Joints of the vertebral column
Muscles of the back
Vessels and nerves of the vertebral column
Anatomy clinical correlates: Anterior and posterior abdominal wall
Anatomy clinical correlates: Bones, joints and muscles of the back
Anatomy clinical correlates: Spinal cord pathways
Anatomy clinical correlates: Vertebral canal
Back pain: Pathology review
Positive and negative predictive value
Sensitivity and specificity
Test precision and accuracy
Type I and type II errors
Anatomy of the breast
Anatomy of the coronary circulation
Anatomy of the heart
Anatomy of the inferior mediastinum
Anatomy of the lungs and tracheobronchial tree
Anatomy of the pleura
Anatomy of the superior mediastinum
Bones and joints of the thoracic wall
Muscles of the thoracic wall
Vessels and nerves of the thoracic wall
Anatomy clinical correlates: Breast
Anatomy clinical correlates: Heart
Anatomy clinical correlates: Mediastinum
Anatomy clinical correlates: Pleura and lungs
Anatomy clinical correlates: Thoracic wall
Cardiovascular system anatomy and physiology
Respiratory system anatomy and physiology
Aortic dissections and aneurysms: Pathology review
Coronary artery disease: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Anatomy of the abdominal viscera: Esophagus and stomach
Anatomy of the abdominal viscera: Large intestine
Anatomy of the abdominal viscera: Small intestine
Anatomy of the gastrointestinal organs of the pelvis and perineum
Gastrointestinal system anatomy and physiology
Enteric nervous system
Colorectal polyps and cancer: Pathology review
Diverticular disease: Pathology review
Laxatives and cathartics
Anatomy of the diaphragm
Anatomy of the larynx and trachea
Anatomy of the lungs and tracheobronchial tree
Anatomy of the nose and paranasal sinuses
Anatomy of the pleura
Bones and joints of the thoracic wall
Muscles of the thoracic wall
Vessels and nerves of the thoracic wall
Anatomy clinical correlates: Pleura and lungs
Anatomy clinical correlates: Thoracic wall
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Lung cancer and mesothelioma: Pathology review
Nasal, oral and pharyngeal diseases: Pathology review
Obstructive lung diseases: Pathology review
Pneumonia: Pathology review
Restrictive lung diseases: Pathology review
Anatomy of the abdominal viscera: Large intestine
Anatomy of the abdominal viscera: Small intestine
Anatomy of the gastrointestinal organs of the pelvis and perineum
Bile secretion and enterohepatic circulation
Enteric nervous system
Gastrointestinal system anatomy and physiology
Inflammatory bowel disease: Pathology review
Malabsorption syndromes: Pathology review
Bacillus cereus (Food poisoning)
Campylobacter jejuni
Clostridium difficile (Pseudomembranous colitis)
Clostridium perfringens
Escherichia coli
Norovirus
Salmonella (non-typhoidal)
Shigella
Staphylococcus aureus
Vibrio cholerae (Cholera)
Yersinia enterocolitica
Anatomy of the heart
Anatomy of the lungs and tracheobronchial tree
Anatomy of the pleura
Anatomy clinical correlates: Heart
Anatomy clinical correlates: Mediastinum
Anatomy clinical correlates: Pleura and lungs
Anatomy clinical correlates: Thoracic wall
Alveolar surface tension and surfactant
Anatomic and physiologic dead space
Breathing cycle and regulation
Diffusion-limited and perfusion-limited gas exchange
Gas exchange in the lungs, blood and tissues
Pulmonary shunts
Regulation of pulmonary blood flow
Respiratory system anatomy and physiology
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Zones of pulmonary blood flow
Cardiac afterload
Cardiac contractility
Cardiac cycle
Cardiac preload
Cardiac work
Frank-Starling relationship
Measuring cardiac output (Fick principle)
Pressure-volume loops
Stroke volume, ejection fraction, and cardiac output
Acid-base map and compensatory mechanisms
Buffering and Henderson-Hasselbalch equation
Physiologic pH and buffers
The role of the kidney in acid-base balance
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Heart failure: Pathology review
Lung cancer and mesothelioma: Pathology review
Obstructive lung diseases: Pathology review
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Pneumonia: Pathology review
Restrictive lung diseases: Pathology review
Tuberculosis: Pathology review
Introduction to the cardiovascular system
Introduction to the lymphatic system
Microcirculation and Starling forces
Cirrhosis: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Heart failure: Pathology review
Hypothyroidism: Pathology review
Nephrotic syndromes: Pathology review
Renal failure: Pathology review
Antidiuretic hormone
Phosphate, calcium and magnesium homeostasis
Potassium homeostasis
Renin-angiotensin-aldosterone system
Sodium homeostasis
Diabetes insipidus and SIADH: Pathology review
Electrolyte disturbances: Pathology review
Parathyroid disorders and calcium imbalance: Pathology review
Anxiety disorders, phobias and stress-related disorders: Pathology Review
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Mood disorders: Pathology review
Psychological sleep disorders: Pathology review
Adrenergic antagonists: Beta blockers
Anticonvulsants and anxiolytics: Barbiturates
Anticonvulsants and anxiolytics: Benzodiazepines
Antihistamines for allergies
Nonbenzodiazepine anticonvulsants
Opioid agonists, mixed agonist-antagonists and partial agonists
Tricyclic antidepressants
Cytokines
Inflammation
Anatomy of the abdominal viscera: Blood supply of the foregut, midgut and hindgut
Anatomy of the abdominal viscera: Esophagus and stomach
Anatomy of the abdominal viscera: Large intestine
Anatomy of the abdominal viscera: Small intestine
Anatomy of the gastrointestinal organs of the pelvis and perineum
Anatomy of the vessels of the posterior abdominal wall
Anatomy clinical correlates: Viscera of the gastrointestinal tract
Gastrointestinal bleeding: Pathology review
Anatomy of the blood supply to the brain
Anatomy of the cranial base
Anatomy of the cranial meninges and dural venous sinuses
Anatomy of the nose and paranasal sinuses
Anatomy of the suboccipital region
Anatomy of the temporomandibular joint and muscles of mastication
Anatomy of the trigeminal nerve (CN V)
Bones of the cranium
Bones of the neck
Deep structures of the neck: Prevertebral muscles
Muscles of the face and scalp
Nerves and vessels of the face and scalp
Superficial structures of the neck: Cervical plexus
Anatomy clinical correlates: Bones, fascia and muscles of the neck
Anatomy clinical correlates: Skull, face and scalp
Anatomy clinical correlates: Temporal regions, oral cavity and nose
Anatomy clinical correlates: Trigeminal nerve (CN V)
Anatomy clinical correlates: Vessels, nerves and lymphatics of the neck
Headaches: Pathology review
Anatomy of the abdominal viscera: Liver, biliary ducts and gallbladder
Anatomy of the abdominal viscera: Pancreas and spleen
Anatomy clinical correlates: Other abdominal organs
Gallbladder histology
Liver histology
Bile secretion and enterohepatic circulation
Liver anatomy and physiology
Pancreatic secretion
Jaundice: Pathology review
Anatomy of the elbow joint
Anatomy of the glenohumeral joint
Anatomy of the hip joint
Anatomy of the knee joint
Anatomy of the radioulnar joints
Anatomy of the sternoclavicular and acromioclavicular joints
Anatomy of the tibiofibular joints
Joints of the ankle and foot
Joints of the wrist and hand
Anatomy clinical correlates: Arm, elbow and forearm
Anatomy clinical correlates: Clavicle and shoulder
Anatomy clinical correlates: Knee
Anatomy clinical correlates: Leg and ankle
Anatomy clinical correlates: Wrist and hand
Gout and pseudogout: Pathology review
Rheumatoid arthritis and osteoarthritis: Pathology review
Seronegative and septic arthritis: Pathology review
Anatomy of the knee joint
Anatomy clinical correlates: Knee
Rheumatoid arthritis and osteoarthritis: Pathology review
Seronegative and septic arthritis: Pathology review
Candida
Clostridium difficile (Pseudomembranous colitis)
Enterobacter
Enterococcus
Escherichia coli
Proteus mirabilis
Pseudomonas aeruginosa
Staphylococcus aureus
Bacterial and viral skin infections: Pathology review
Skin histology
Skin anatomy and physiology
Acneiform skin disorders: Pathology review
Papulosquamous and inflammatory skin disorders: Pathology review
Pigmentation skin disorders: Pathology review
Skin cancer: Pathology review
Vesiculobullous and desquamating skin disorders: Pathology review
Anatomy of the heart
Anatomy of the vagus nerve (CN X)
Aortic dissections and aneurysms: Pathology review
Cardiomyopathies: Pathology review
Coronary artery disease: Pathology review
Heart blocks: Pathology review
Supraventricular arrhythmias: Pathology review
Valvular heart disease: Pathology review
Ventricular arrhythmias: Pathology review
Hunger and satiety
Anxiety disorders, phobias and stress-related disorders: Pathology Review
Breast cancer: Pathology review
Colorectal polyps and cancer: Pathology review
Dementia: Pathology review
Diabetes mellitus: Pathology review
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Heart failure: Pathology review
HIV and AIDS: Pathology review
Hyperthyroidism: Pathology review
Inflammatory bowel disease: Pathology review
Jaundice: Pathology review
Lung cancer and mesothelioma: Pathology review
Malabsorption syndromes: Pathology review
Mood disorders: Pathology review
Tuberculosis: Pathology review

Transcript

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As a society, we rely on complex transportation networks in order to supply and transport important goods and materials. The same idea goes for the human body.

Here, the circulatory systems form a complex transportation network, which allows movement of important materials, such as oxygen, around the body.

This circulatory system has two divisions: the cardiovascular system and the lymphatic system. Now, let’s get our blood flowing and focus on the cardiovascular system!

The term “cardiovascular” can be broken down into cardio-, meaning heart, and -vascular, meaning blood vessels. So, the cardiovascular system consists of the heart and blood vessels, which together make up the blood transportation network of the body that carries nutrients, oxygen and waste products to and from cells.

The heart is a muscular organ that lies in the chest, and it pumps blood through the network of blood vessels in the body. It’s composed of four chambers: a right and left atrium, as well as a right and left ventricle.

Next are the blood vessels, which are tube-like structures that carry the blood being pumped by the heart. Arteries are the blood vessels that carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, and veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart.

The blood running through these blood vessels also carry signaling molecules, called hormones, which allow for communication between organs and organ systems.

Lastly, blood helps regulate body temperature. For example, when it's really cold outside, the blood vessels lying close to the skin constrict to reduce blood flow, saving the heat within the body.

Now, there are two main networks, called the pulmonary and systemic circulation, that allow for blood circulation between the heart and the tissues in our body.

In the pulmonary circulation, oxygen-depleted blood from body tissues runs from the right atrium to the right ventricle of the heart into the right and left pulmonary arteries, which carry the blood into the right and left lungs.

This is the one exception where arteries carry oxygen-depleted blood. Here, the blood dumps carbon dioxide and receives fresh oxygen via gas exchange.

Then, the blood runs back through four pulmonary veins to the left atrium, where it passes into the left ventricle. This is the one exception where veins carry oxygen-rich blood.

Now, this is where the systemic circulation begins, pumping oxygen-rich blood into the body’s largest artery, called the aorta. Along its course, the aorta gives off smaller arteries that gradually branch into smaller vessels called arterioles.

Near the body tissues, these arterioles further divide into smaller vessels called capillaries. These capillaries form small networks called capillary beds, in which blood flow is reduced. This reduction in blood flow allows the exchange of gases, nutrients and waste products between the blood and tissues.

Now, after this interchange of substances occurs, the capillaries regroup to form venules, which eventually drain into veins, and eventually into the two largest veins called the superior vena cava and the inferior vena cava, which collect blood from the entire body and empty into the right atrium. And once more, the pulmonary circulation cycle restarts.

Ok, now let’s pause for a second and see if you can identify the chambers of the heart and the course of blood through the pulmonary and systemic circulations.

Key Takeaways

The cardiovascular system is a series of organs that work together to circulate blood throughout the body. It includes the heart, which pumps blood through blood vessels; namely the veins, arteries, and capillaries.

Arteries generally carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, whereas veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart. The capillaries are tiny vessels that allow nutrients and oxygen from the blood to diffuse into surrounding tissues.

Sources

  1. "Clinically Oriented Anatomy" Lippincott Williams & Wilkins (2013)
  2. "Atlas of Human Anatomy" Saunders/Elsevier (2014)
  3. "Introduction to the Lymphatic System" National Cancer Institute SEER Training Modules