Introduction to the cardiovascular system

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Introduction to the cardiovascular system

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Introduction to the skeletal system
Introduction to the cardiovascular system
Introduction to the muscular system
Anatomical terminology
Anatomy of the muscles and nerves of the posterior abdominal wall
Anatomy of the abdominal viscera: Innervation of the abdominal viscera
Enteric nervous system
Physiological changes during exercise
Pentose phosphate pathway
Glycolysis
Electron transport chain and oxidative phosphorylation
Development of the face and palate
Pharyngeal arches, pouches, and clefts
Development of the teeth
Development of the tongue
Citric acid cycle
Gluconeogenesis
Nitrogen and urea cycle
Amino acid metabolism
Fatty acid synthesis
Ketone body metabolism
Fatty acid oxidation
Cholesterol metabolism
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
Glycogen storage disease type III
Glycogen storage disease type IV
Glycogen storage disease type V
Gaucher disease (NORD)
Cystinosis
Ornithine transcarbamylase deficiency
Familial hypercholesterolemia
Disorders of carbohydrate metabolism: Pathology review
Dyslipidemias: Pathology review
Glycogen storage disorders: Pathology review
Disorders of fatty acid metabolism: Pathology review
Lysosomal storage disorders: Pathology review
Disorders of amino acid metabolism: Pathology review
Carbohydrates and sugars
Proteins
Fats and lipids
Vitamin B12 deficiency
Fat-soluble vitamin deficiency and toxicity: Pathology review
Water-soluble vitamin deficiency and toxicity: B1-B7: Pathology review
Zinc deficiency and protein-energy malnutrition: Pathology review
Nernst equation
Nernst equation
Peroxisomal disorders: Pathology review
Peroxisomal disorders: Pathology review
Nuclear structure
Nuclear structure
Amino acids and protein folding
Amino acids and protein folding
Nucleotide metabolism
Nucleotide metabolism
Mitosis and meiosis
Mitosis and meiosis
Adenosine deaminase deficiency
Adenosine deaminase deficiency
Purine and pyrimidine synthesis and metabolism disorders: Pathology review
Purine and pyrimidine synthesis and metabolism disorders: Pathology review
Polymerase chain reaction (PCR) and reverse-transcriptase PCR (RT-PCR)
Polymerase chain reaction (PCR) and reverse-transcriptase PCR (RT-PCR)
ELISA (Enzyme-linked immunosorbent assay)
DNA cloning
Fluorescence in situ hybridization
Gel electrophoresis and genetic testing
Lactose intolerance
Down syndrome (Trisomy 21)
Edwards syndrome (Trisomy 18)
Patau syndrome (Trisomy 13)
Huntington disease
Fragile X syndrome
Myotonic dystrophy
Friedreich ataxia
Prader-Willi syndrome
Angelman syndrome
Polycystic kidney disease
Familial adenomatous polyposis
Alpha-thalassemia
Beta-thalassemia
Miscellaneous genetic disorders: Pathology review
Muscular dystrophies and mitochondrial myopathies: Pathology review
Autosomal trisomies: Pathology review
Mitochondrial myopathy
Gestational diabetes
Placental abruption
Preeclampsia & eclampsia
Fetal alcohol syndrome
Testicular tumors: Pathology review
Disorders of sex chromosomes: Pathology review
Prostate disorders and cancer: Pathology review
Uterine disorders: Pathology review
Cervical cancer: Pathology review
Ovarian cysts and tumors: Pathology review
Vaginal and vulvar disorders: Pathology review
Breast cancer: Pathology review
Congenital TORCH infections: Pathology review
Disorders of sexual development and sex hormones: Pathology review
Complications during pregnancy: Pathology review
Amenorrhea: Pathology review
Adrenergic antagonists: Alpha blockers
Androgens and antiandrogens
PDE5 inhibitors
Aromatase inhibitors
Uterine stimulants and relaxants
Estrogens and antiestrogens
Progestins and antiprogestins

Transcript

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As a society, we rely on complex transportation networks in order to supply and transport important goods and materials. The same idea goes for the human body.

Here, the circulatory systems form a complex transportation network, which allows movement of important materials, such as oxygen, around the body.

This circulatory system has two divisions: the cardiovascular system and the lymphatic system. Now, let’s get our blood flowing and focus on the cardiovascular system!

The term “cardiovascular” can be broken down into cardio-, meaning heart, and -vascular, meaning blood vessels. So, the cardiovascular system consists of the heart and blood vessels, which together make up the blood transportation network of the body that carries nutrients, oxygen and waste products to and from cells.

The heart is a muscular organ that lies in the chest, and it pumps blood through the network of blood vessels in the body. It’s composed of four chambers: a right and left atrium, as well as a right and left ventricle.

Next are the blood vessels, which are tube-like structures that carry the blood being pumped by the heart. Arteries are the blood vessels that carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, and veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart.

The blood running through these blood vessels also carry signaling molecules, called hormones, which allow for communication between organs and organ systems.

Lastly, blood helps regulate body temperature. For example, when it's really cold outside, the blood vessels lying close to the skin constrict to reduce blood flow, saving the heat within the body.

Now, there are two main networks, called the pulmonary and systemic circulation, that allow for blood circulation between the heart and the tissues in our body.

In the pulmonary circulation, oxygen-depleted blood from body tissues runs from the right atrium to the right ventricle of the heart into the right and left pulmonary arteries, which carry the blood into the right and left lungs.

This is the one exception where arteries carry oxygen-depleted blood. Here, the blood dumps carbon dioxide and receives fresh oxygen via gas exchange.

Then, the blood runs back through four pulmonary veins to the left atrium, where it passes into the left ventricle. This is the one exception where veins carry oxygen-rich blood.

Now, this is where the systemic circulation begins, pumping oxygen-rich blood into the body’s largest artery, called the aorta. Along its course, the aorta gives off smaller arteries that gradually branch into smaller vessels called arterioles.

Near the body tissues, these arterioles further divide into smaller vessels called capillaries. These capillaries form small networks called capillary beds, in which blood flow is reduced. This reduction in blood flow allows the exchange of gases, nutrients and waste products between the blood and tissues.

Now, after this interchange of substances occurs, the capillaries regroup to form venules, which eventually drain into veins, and eventually into the two largest veins called the superior vena cava and the inferior vena cava, which collect blood from the entire body and empty into the right atrium. And once more, the pulmonary circulation cycle restarts.

Ok, now let’s pause for a second and see if you can identify the chambers of the heart and the course of blood through the pulmonary and systemic circulations.

Key Takeaways

The cardiovascular system is a series of organs that work together to circulate blood throughout the body. It includes the heart, which pumps blood through blood vessels; namely the veins, arteries, and capillaries.

Arteries generally carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, whereas veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart. The capillaries are tiny vessels that allow nutrients and oxygen from the blood to diffuse into surrounding tissues.

Sources

  1. "Clinically Oriented Anatomy" Lippincott Williams & Wilkins (2013)
  2. "Atlas of Human Anatomy" Saunders/Elsevier (2014)
  3. "Introduction to the Lymphatic System" National Cancer Institute SEER Training Modules