Osmosis video - Alagille syndrome (NORD)

Alagille syndrome (NORD) is a rare, autosomal dominant disorder that affects the liver, heart, and other parts of the body. The most common symptom of Alagille syndrome is jaundice (yellowing of the skin and eyes) in infancy. Other symptoms may include malformed bones, kidney problems, and irregular developmental milestones. There is no cure for Alagille syndrome, but many affected individuals can lead normal, productive lives with proper care.