Osmosis video - Limited systemic sclerosis (CREST syndrome)

CREST syndrome, also known as the limited cutaneous form of systemic sclerosis is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. It is associated with detectable antibodies against centromeres, and usually spares the kidneys. If the lungs are involved, it is usually in the form of pulmonary arterial hypertension.