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Tropical sprue is a condition that affects the small intestine and is characterized by malabsorption of nutrients, particularly vitamin B12 and folate. It is thought to be due to bacterial overgrowth, most commonly of Klebsiella, E. coli, and Enterobacter species. Symptoms of tropical sprue may include diarrhea, weight loss, anemia, abdominal pain, bloating, and fatigue. Treatment for tropical sprue typically involves using antibiotics to reduce bacterial overgrowth, and nutrition replacement to deal with specific deficiencies like folate and Vitamin B12.
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