Absorption atelectasis occurs when small pockets of air remain trapped within non-ventilated alveoli. The oxygen and carbon dioxide within these alveoli are gradually reabsorbed into the pulmonary circulation, which causes the alveoli to collapse, and subsequently, collapse of a portion of the lung.
Absorption atelectasis often happens due to a blockage of the airways between the alveoli and the trachea, the tube that carries air to and from the lungs. Common causes of airway obstruction include mucus plugs, foreign objects, or tumors, all of which prevent the entry of fresh air into the lungs.
In the absence of airway obstruction, absorption atelectasis can occur in individuals who receive high concentrations of supplemental oxygen. This is frequently the case for individuals undergoing general anesthesia. During 100% oxygen delivery, most of the air within the lungs is washed out and replaced with oxygen, which is readily absorbed into the
pulmonary capillaries. The rapid diffusion of oxygen may lead to insufficient amounts of air left inside the alveoli to keep them inflated, resulting in collapse of the
alveolar walls. Blood that flows through areas of the lung containing these collapsed alveoli will encounter no oxygen to absorb.