Bipolar and related disorders

Last updated: October 11, 2024

Bipolar and related disorders

to do

to do

Ornithine transcarbamylase deficiency
Homocystinuria
Glycolysis
Glycogen metabolism
Gluconeogenesis
Pentose phosphate pathway
Parvovirus B19
Hepatitis C virus
HIV (AIDS)
Hepatitis medications
Herpesvirus medications
Mechanisms of antibiotic resistance
Cerebral circulation
Neuron action potential
Subdural hematoma
Intracerebral hemorrhage
Epidural hematoma
Subarachnoid hemorrhage
Central pontine myelinolysis
Pituitary adenoma
Neurogenic bladder
Tuberous sclerosis
Pressures in the cardiovascular system
Resistance to blood flow
Cardiac work
Changes in pressure-volume loops
Physiological changes during exercise
Action potentials in myocytes
Action potentials in pacemaker cells
Baroreceptors
Chemoreceptors
ECG QRS transition
ECG axis
Coarctation of the aorta
Cushing syndrome
Patent ductus arteriosus
Long QT syndrome and Torsade de pointes
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Heart failure
Cardiac tamponade
Electron transport chain and oxidative phosphorylation
Reading a chest X-ray
Ventilation-perfusion ratios and V/Q mismatch
Acute respiratory distress syndrome
Methemoglobinemia
Pulmonary embolism
Pulmonary hypertension
Pleural effusion
Complement system
Abnormal heart sounds
Free radicals and cellular injury
Androgen insensitivity syndrome
Polycystic ovary syndrome
Androgens and antiandrogens
Aromatase inhibitors
Mechanisms of antibiotic resistance
Bile secretion and enterohepatic circulation
Pneumothorax
Cardiac excitation-contraction coupling
Insulin
Hypoprolactinemia
Diabetes mellitus: Pathology review
Diabetes mellitus
Osmoregulation
Molarity and dilutions
Mitochondrial myopathy
Bordetella pertussis (Whooping cough)
Viral structure and functions
Hepatitis A and Hepatitis E virus
HIV (AIDS)
5-alpha-reductase deficiency
Delayed puberty
Bone tumors
Bone histology
Bone remodeling and repair
Selective serotonin reuptake inhibitors
Tricyclic antidepressants
Monoamine oxidase inhibitors
Serotonin and norepinephrine reuptake inhibitors
Bipolar and related disorders
Cocaine use disorder
Opioid use disorder
Cannabis use disorder
Alcohol use disorder
Autism spectrum disorder
Hardy-Weinberg equilibrium
Inheritance patterns
Mendelian genetics and punnett squares
DNA structure
Transcription of DNA
Translation of mRNA
Gene regulation
Amino acids and protein folding
DNA mutations
Gel electrophoresis and genetic testing

Flashcards

Bipolar and related disorders

0 of 7 complete

Transcript

Watch video only

Contributors

Maybe you’ve heard the term “bipolar” used flippantly to describe someone who’s moody, or who has mood swings, but the colloquial use of the term is really different from clinically diagnosed bipolar disorder. Bipolar disorder, which used to be called manic depression, is a serious mental disorder that causes a person to have dramatic shifts in emotions, mood, and energy levels: moving from extreme lows to extreme highs. But these shifts don’t happen moment to moment—they usually happen over several days or weeks. Now, bipolar and related disorders include several different conditions, but the most important ones are bipolar I disorder, bipolar II disorder, and cyclothymic disorder.

Now, let’s cover some important clinical features associated with these conditions. The first one is a major depressive episode, which is characterized by the low moods that are identical to those in a related disorder: major depressive disorder, also known as unipolar depression. During major depressive episodes, individuals can feel hopeless and discouraged, lack energy and mental focus, and can have physical symptoms like eating and sleeping too much or too little.

But along with these lows, the thing that sets bipolar disorders apart from unipolar depression is that individuals can have periods of high moods, which are called manic episodes or hypomanic episodes, depending on their level of severity.

Manic episodes are described as an abnormally elevated mood that lasts for at least one week or requires hospitalization. In a manic state, people can feel energetic, overly happy or optimistic, euphoric with really high self-esteem, or even unusually irritable.

And on the surface, these might seem like very positive characteristics, but when an individual is in a full manic episode, these symptoms can reach a dangerous extreme. A person experiencing mania might invest all of their money in a risky business venture or behave recklessly.

Individuals might talk pressured speech, where they talk constantly at a rapid-fire pace, or they might have racing thoughts and might feel “wired,” as if they don’t need sleep.

Manic episodes can also include delusions of grandeur: for example, they might believe that they are on a personal mission from god, or that they have supernatural powers. And they might make poor decisions without any regard for later consequences.

On the flip side, hypomanic episodes are described as an abnormally elevated mood that lasts for at least 4 consecutive days and doesn’t require hospitalization.

In a hypomanic state, individuals experience similar symptoms and feelings to the ones seen during manic episodes, but it's important to note that they are milder in severity. Additionally, there are no psychotic features.

Between major depressive episodes and manic or hypomanic episodes, individuals usually have a relatively stable mood, which is often described as euthymia.

One way to understand these swings is by charting them on a graph. So let’s say the y-axis is mood, with mania and depression being on the far ends of the axis, and the x-axis is time. A neurotypical person (someone without a mental health disorder) might have normal ups and downs throughout their life, and they might even have some pretty serious lows once in a while, maybe after losing a job or moving to a new place and feeling lonely.

Now, the diagnosis of bipolar I disorder includes at least one manic episode, which may be preceded or followed by hypomanic or major depressive episodes.

On the flip side, the diagnosis of bipolar II disorder includes at least one hypomanic and one major depressive episode, but no manic episodes.

Finally, the diagnosis of cyclothymic disorder is based on frequent hypomanic and depressive symptoms over a 2-year period, which are not as severe as the ones seen in bipolar I and bipolar II disorders. The symptoms must be present for at least half the time, meaning at least one year, and there shouldn’t be a period without symptoms for more than 2 months.

Now, sometimes, these conditions can be further described by additional clinical features, also known as specifiers.

For example, some individuals might have bipolar disorder with anxious distress, so they might complain of feeling restless or experiencing fear that something terrible might happen.