Cauda equina syndrome

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Cauda equina syndrome

Unit 7 Nervous

Unit 7 Nervous

Headaches: Clinical
Headaches: Pathology review
Migraine medications
Migraine
Central nervous system histology
Peripheral nervous system histology
Development of the nervous system
Ascending and descending spinal tracts
Brown-Sequard Syndrome
Syringomyelia
Anatomy of the trigeminal nerve (CN V)
Anatomy of the basal ganglia
Anatomy of the white matter tracts
Anatomy clinical correlates: Vertebral canal
Anatomy of the cerebral cortex
Anatomy of the cerebellum
Basal ganglia: Direct and indirect pathway of movement
Cerebrospinal fluid
Blood brain barrier
Dandy-Walker malformation
Intracerebral hemorrhage
Subdural hematoma
Epidural hematoma
Subarachnoid hemorrhage
Shaken baby syndrome
Normal pressure hydrocephalus
Huntington disease
Movement disorders: Pathology review
Anti-parkinson medications
Parkinson disease
Cluster headache
Tension headache
Chiari malformation
Spina bifida
Cerebral circulation
Cerebellum
Glaucoma
Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review
Anatomy and physiology of the eye
Anatomy of the eye
Anatomy of the oculomotor (CN III), trochlear (CN IV) and abducens (CN VI) nerves
Eye and ear histology
Anatomy and physiology of the ear
Auditory transduction and pathways
Vestibular transduction
Vertigo: Pathology review
Dizziness and vertigo: Clinical
Otitis media
Pediatric ear, nose, and throat conditions: Clinical
Optic pathways and visual fields
Photoreception
Eye conditions: Retinal disorders: Pathology review
Eye conditions: Inflammation, infections and trauma: Pathology review
Taste and the tongue
Olfactory transduction and pathways
Anatomy of the tongue
Meningitis
Meningitis, encephalitis and brain abscesses: Clinical
Neisseria meningitidis
Mumps virus
Herpes simplex virus
Poliovirus
West Nile virus
West Nile Virus Infection
Trypanosoma cruzi (Chagas disease)
Seizures and epilepsy
Early infantile epileptic encephalopathy (NORD)
Febrile seizure
Seizures: Clinical
Seizures: Pathology review
Nonbenzodiazepine anticonvulsants
Anticonvulsants and anxiolytics: Benzodiazepines
Anticonvulsants and anxiolytics: Barbiturates
Cranial nerves
Cranial nerves rap
Introduction to the cranial nerves
Cranial nerve pathways
Brain tumors: Clinical
Pediatric brain tumors: Pathology review
Adult brain tumors: Pathology review
Knowledge Shot: Glioblastoma
Adult brain tumors
Tuberous sclerosis
von Hippel-Lindau disease
Neurofibromatosis
Anatomy of the limbic system
Schizophrenia
Schizophrenia spectrum disorders: Clinical
Schizophrenia spectrum disorders: Pathology review
Anatomy of the vertebral canal
Anatomy clinical correlates: Spinal cord pathways
Anatomy of the olfactory (CN I) and optic (CN II) nerves
Anatomy of the facial nerve (CN VII)
Anatomy of the glossopharyngeal nerve (CN IX)
Anatomy of the spinal accessory (CN XI) and hypoglossal (CN XII) nerves
Anatomy of the vagus nerve (CN X)
Ischemic stroke
Restless legs syndrome
Acoustic neuroma (schwannoma)
Pediatric brain tumors
Pituitary adenoma
Cauda equina syndrome
Neonatal meningitis
Encephalitis
Bell palsy
Cerebral vascular disease: Pathology review
Spinal cord disorders: Pathology review
Dementia: Pathology review
Anatomy of the inner ear
Emotion
Stroke: Clinical
Broca aphasia
Wernicke aphasia
Delirium
Dementia and delirium: Clinical
Medications for neurodegenerative diseases
General anesthetics
Sleep
Dementia with Lewy bodies
Tricyclic antidepressants
Alzheimer disease
Frontotemporal dementia

Transcript

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Cauda equina syndrome is a condition caused by damage to the bundle of peripheral nerves protruding from the bottom of the spinal cord, called the cauda equina.

The latin words cauda equina mean horse’s tail, which is what early anatomists thought this nerve bundle looked like.

The spinal column is made of individual bones, called vertebrae.

Each vertebra is made of a large anterior portion called the body, and the posterior part called the vertebral arch.

The central cavity between the body and the arch is called the vertebral foramen.

Now the spinal column is made of 33 vertebrae: 7 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 4 coccygeal.

Other than C1 and C2, each two adjacent vertebrae are, separated by an intervertebral disc, which allows for a slight movement of the vertebrae, and acts as a shock absorber.

The sacral and coccygeal vertebrae are fused together to form the sacral bone and coccyx, or tailbone respectively.

Now if you cut the spinal column in half lengthwise you can see that all the vertebral foramina together form the vertebral, or the spinal canal, which is occupied by the spinal cord.

The spinal cord is connected to the brain and travels through the spinal canal to the second lumbar vertebra, where it ends in a cone, called conus medullaris.

There are 31 pairs of nerves originating from the spinal cord called spinal nerves; there are 8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal.

Each nerve leaves the spinal canal through the corresponding intervertebral foramen, which are openings between two adjacent vertebrae.

Since the spinal cord is shorter than the spinal canal, the nerves of the lumbar, sacral and coccygeal regions have to travel down the spinal canal to reach their corresponding openings, forming a nerve bundle below the spinal cord called the cauda equina.

These nerves carry motor innervation for the genitals, both internal and external anal sphincter, detrusor vesicae, which is a muscle in the bladder that contracts during urination, and muscles of the leg.

They are in charge of the knee and ankle reflexes.

Skin sensations of the legs and pelvis are also carried by these nerves.

Cauda equina syndrome is caused by compression, trauma, or damage to multiple nerves of the cauda equina.

Large lumbar disc herniation is the most common cause of cauda equina syndrome.

And poor posture, traumas, physical activity, and strong rotational movement can cause herniations where the intervertebral disc bulges out and compress the nerves or spinal cord.

This is similar to sciatica, but the herniation is usually larger, and more nerves are compressed, including those that control the bladder and reproductive organs.

Compression can also be caused by spinal stenosis which is the narrowing of the vertebral foramen in the lumbar vertebrae.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
  4. "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
  5. "Cauda Equina Syndrome" Journal of Pain & Palliative Care Pharmacotherapy (2014)
  6. "Cauda Equina Syndrome Due to Lumbar Disc Herniation: a Review of Literature" Folia Medica (2017)