Cauda equina syndrome

Cauda equina syndrome

Neuro

Neuro

Spinal cord disorders: Pathology review
Congenital neurological disorders: Pathology review
Brown-Sequard Syndrome
Syringomyelia
Chiari malformation
Cauda equina syndrome
Demyelinating disorders: Pathology review
Multiple sclerosis
Transverse myelitis
Central pontine myelinolysis
Acute disseminated encephalomyelitis
Guillain-Barre syndrome
JC virus (Progressive multifocal leukoencephalopathy)
Auditory transduction and pathways
Anatomy and physiology of the ear
Vestibulo-ocular reflex and nystagmus
Vestibular transduction
Anatomy and physiology of the eye
Photoreception
Optic pathways and visual fields
Olfactory transduction and pathways
Taste and the tongue
Migraine
Migraine medications
Headaches: Clinical
Glaucoma
Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review
Eye conditions: Retinal disorders: Pathology review
Eye conditions: Inflammation, infections and trauma: Pathology review
Age-related macular degeneration
Diabetic retinopathy
Cataract
Pediatric ear, nose, and throat conditions: Clinical
Sensory system: Eye and ear disorders
Hypokinetic movement disorders: Clinical
Hyperkinetic movement disorders: Clinical
Parkinson disease
Huntington disease
Charcot-Marie-Tooth disease
Myalgias and myositis: Pathology review
Inflammatory myopathies: Clinical
Inclusion body myopathy
Polymyositis
Dermatomyositis
Amyotrophic lateral sclerosis
Spinal muscular atrophy
Muscular dystrophies and mitochondrial myopathies: Pathology review
Myotonic dystrophy
Muscular dystrophy
Neuromuscular junction disorders: Pathology review
Myasthenia gravis
Lambert-Eaton myasthenic syndrome
Muscle weakness: Clinical
Seizures: Pathology review
Seizures: Clinical
Seizures and epilepsy
Adrenoleukodystrophy (NORD)
Leukodystrophy
Metachromatic leukodystrophy (NORD)
Tuberous sclerosis
Neurofibromatosis
Cerebral palsy
Neurocutaneous disorders: Pathology review
Dementia: Pathology review
Alzheimer disease
Dementia with Lewy bodies
Frontotemporal dementia
Vascular dementia
Normal pressure hydrocephalus
Delirium
Anatomy of the limbic system
Anatomy of the basal ganglia
Basal ganglia: Direct and indirect pathway of movement
Anatomy of the brainstem
Anatomy of the brachial plexus
Pediatric brain tumors: Pathology review
Adult brain tumors: Pathology review

Transcript

Watch video only

Cauda equina syndrome is a condition caused by damage to the bundle of peripheral nerves protruding from the bottom of the spinal cord, called the cauda equina.

The latin words cauda equina mean horse’s tail, which is what early anatomists thought this nerve bundle looked like.

The spinal column is made of individual bones, called vertebrae.

Each vertebra is made of a large anterior portion called the body, and the posterior part called the vertebral arch.

The central cavity between the body and the arch is called the vertebral foramen.

Now the spinal column is made of 33 vertebrae: 7 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 4 coccygeal.

Other than C1 and C2, each two adjacent vertebrae are, separated by an intervertebral disc, which allows for a slight movement of the vertebrae, and acts as a shock absorber.

The sacral and coccygeal vertebrae are fused together to form the sacral bone and coccyx, or tailbone respectively.

Now if you cut the spinal column in half lengthwise you can see that all the vertebral foramina together form the vertebral, or the spinal canal, which is occupied by the spinal cord.

The spinal cord is connected to the brain and travels through the spinal canal to the second lumbar vertebra, where it ends in a cone, called conus medullaris.

There are 31 pairs of nerves originating from the spinal cord called spinal nerves; there are 8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal.

Each nerve leaves the spinal canal through the corresponding intervertebral foramen, which are openings between two adjacent vertebrae.

Since the spinal cord is shorter than the spinal canal, the nerves of the lumbar, sacral and coccygeal regions have to travel down the spinal canal to reach their corresponding openings, forming a nerve bundle below the spinal cord called the cauda equina.

These nerves carry motor innervation for the genitals, both internal and external anal sphincter, detrusor vesicae, which is a muscle in the bladder that contracts during urination, and muscles of the leg.

They are in charge of the knee and ankle reflexes.

Skin sensations of the legs and pelvis are also carried by these nerves.

Cauda equina syndrome is caused by compression, trauma, or damage to multiple nerves of the cauda equina.

Large lumbar disc herniation is the most common cause of cauda equina syndrome.

And poor posture, traumas, physical activity, and strong rotational movement can cause herniations where the intervertebral disc bulges out and compress the nerves or spinal cord.

This is similar to sciatica, but the herniation is usually larger, and more nerves are compressed, including those that control the bladder and reproductive organs.

Compression can also be caused by spinal stenosis which is the narrowing of the vertebral foramen in the lumbar vertebrae.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
  4. "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
  5. "Cauda Equina Syndrome" Journal of Pain & Palliative Care Pharmacotherapy (2014)
  6. "Cauda Equina Syndrome Due to Lumbar Disc Herniation: a Review of Literature" Folia Medica (2017)