Development of the nervous system

Summary of Development of the nervous system
The developing brain is divided into three sections: prosencephalon, mesencephalon, and rhombencephalon, also known as forebrain, midbrain, and hindbrain, respectively. The prosencephalon will give rise to the telencephalon, the future cortex and basal ganglia, and the diencephalon, which will evolve into the optic cup, thalamus, hypothalamus, and mammillary bodies. The mesencephalon will become the tectum, cerebral aqueduct, red nucleus, the substantia nigra and the crus cerebri. The rhombencephalon will generate the metencephalon, the future pons and cerebellum, and the myelencephalon, which will become the medulla oblongata.

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Development of the nervous system

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Development of the nervous system

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The genes establish the differentiation of the cerebellum and of the roof of the midbrain.

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A male newborn has microcephaly, ocular hypotelorism, midfacial hypoplasia, and cleft lip and palate. He was delivered at 38 weeks' gestation to a 28-year-old primigravid woman after an uncomplicated labor and delivery. The mother denies any history of serious illness but did not receive regular prenatal care. Which of the following is the most likely cause of this child's deformity?