Introduction to the cardiovascular system

Last updated: September 12, 2024

Introduction to the cardiovascular system

Cardiovascular System

Cardiovascular System

Introduction to the cardiovascular system
Anatomy of the coronary circulation
Anatomy clinical correlates: Heart
Anatomy of the superior mediastinum
Anatomy of the inferior mediastinum
Anatomy clinical correlates: Mediastinum
Development of the cardiovascular system
Fetal circulation
Cardiac muscle histology
Artery and vein histology
Arteriole, venule and capillary histology
Lymphatic system anatomy and physiology
Blood pressure, blood flow, and resistance
Pressures in the cardiovascular system
Laminar flow and Reynolds number
Resistance to blood flow
Compliance of blood vessels
Control of blood flow circulation
Microcirculation and Starling forces
Measuring cardiac output (Fick principle)
Stroke volume, ejection fraction, and cardiac output
Cardiac contractility
Frank-Starling relationship
Cardiac preload
Cardiac afterload
Law of Laplace
Cardiac and vascular function curves
Altering cardiac and vascular function curves
Cardiac cycle
Cardiac work
Pressure-volume loops
Changes in pressure-volume loops
Physiological changes during exercise
Cardiovascular changes during hemorrhage
Cardiovascular changes during postural change
Normal heart sounds
Abnormal heart sounds
Action potentials in myocytes
Action potentials in pacemaker cells
Excitability and refractory periods
Cardiac excitation-contraction coupling
Cardiac conduction system
Cardiac conduction velocity
ECG basics
ECG rate and rhythm
ECG intervals
ECG QRS transition
ECG axis
ECG normal sinus rhythm
ECG cardiac infarction and ischemia
ECG cardiac hypertrophy and enlargement
Baroreceptors
Chemoreceptors
Renin-angiotensin-aldosterone system
Arterial disease
Angina pectoris
Stable angina
Unstable angina
Myocardial infarction
Prinzmetal angina
Coronary steal syndrome
Peripheral artery disease
Subclavian steal syndrome
Aneurysms
Aortic dissection
Vasculitis
Behcet's disease
Kawasaki disease
Hypertension
Hypertensive emergency
Renal artery stenosis
Coarctation of the aorta
Cushing syndrome
Conn syndrome
Pheochromocytoma
Polycystic kidney disease
Hypotension
Orthostatic hypotension
Abetalipoproteinemia
Familial hypercholesterolemia
Hypertriglyceridemia
Hyperlipidemia
Chronic venous insufficiency
Thrombophlebitis
Deep vein thrombosis
Lymphedema
Lymphangioma
Shock
Vascular tumors
Human herpesvirus 8 (Kaposi sarcoma)
Angiosarcomas
Persistent truncus arteriosus
Transposition of the great vessels
Total anomalous pulmonary venous return
Tetralogy of Fallot
Hypoplastic left heart syndrome
Patent ductus arteriosus
Ventricular septal defect
Atrial septal defect
Atrial flutter
Atrial fibrillation
Premature atrial contraction
Atrioventricular nodal reentrant tachycardia (AVNRT)
Wolff-Parkinson-White syndrome
Ventricular tachycardia
Brugada syndrome
Premature ventricular contraction
Long QT syndrome and Torsade de pointes
Ventricular fibrillation
Atrioventricular block
Bundle branch block
Pulseless electrical activity
Tricuspid valve disease
Pulmonary valve disease
Mitral valve disease
Aortic valve disease
Dilated cardiomyopathy
Restrictive cardiomyopathy
Hypertrophic cardiomyopathy
Heart failure
Cor pulmonale
Endocarditis
Myocarditis
Rheumatic heart disease
Pericarditis and pericardial effusion
Cardiac tamponade
Dressler syndrome
Cardiac tumors
Acyanotic congenital heart defects: Pathology review
Cyanotic congenital heart defects: Pathology review
Atherosclerosis and arteriosclerosis: Pathology review
Coronary artery disease: Pathology review
Peripheral artery disease: Pathology review
Valvular heart disease: Pathology review
Cardiomyopathies: Pathology review
Heart failure: Pathology review
Supraventricular arrhythmias: Pathology review
Ventricular arrhythmias: Pathology review
Heart blocks: Pathology review
Aortic dissections and aneurysms: Pathology review
Pericardial disease: Pathology review
Endocarditis: Pathology review
Hypertension: Pathology review
Shock: Pathology review
Vasculitis: Pathology review
Cardiac and vascular tumors: Pathology review
Dyslipidemias: Pathology review
Sympatholytics: Alpha-2 agonists
Adrenergic antagonists: Presynaptic
Adrenergic antagonists: Alpha blockers
Adrenergic antagonists: Beta blockers
ACE inhibitors, ARBs and direct renin inhibitors
Thiazide and thiazide-like diuretics
Calcium channel blockers
cGMP mediated smooth muscle vasodilators
Class I antiarrhythmics: Sodium channel blockers
Class II antiarrhythmics: Beta blockers
Class III antiarrhythmics: Potassium channel blockers
Class IV antiarrhythmics: Calcium channel blockers and others
Lipid-lowering medications: Statins
Lipid-lowering medications: Fibrates
Miscellaneous lipid-lowering medications
Positive inotropic medications
Cardiomyopathies: Clinical
Congenital heart defects: Clinical
Valvular heart disease: Clinical
Infective endocarditis: Clinical
Pericardial disease: Clinical
Chest trauma: Clinical
Hypertension: Clinical
Pulmonary hypertension
Aortic aneurysms and dissections: Clinical
Raynaud phenomenon
Peripheral vascular disease: Clinical
Heart failure: Clinical
Coronary artery disease: Clinical
Deep vein thrombosis and pulmonary embolism: Pathology review
Fascia, vessels and nerves of the upper limb
Vessels and nerves of the forearm
Vessels and nerves of the hand
Anatomy of the abdominal viscera: Blood supply of the foregut, midgut and hindgut
Fascia, vessels and nerves of the lower limb
Vessels and nerves of the gluteal region and posterior thigh
Anatomy of the popliteal fossa
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Gas exchange in the lungs, blood and tissues
Oxygen binding capacity and oxygen content
Oxygen-hemoglobin dissociation curve
Carbon dioxide transport in blood
Trypanosoma cruzi (Chagas disease)
Yellow fever virus
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Arteriovenous malformation
Cerebral circulation

Transcript

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As a society, we rely on complex transportation networks in order to supply and transport important goods and materials. The same idea goes for the human body.

Here, the circulatory systems form a complex transportation network, which allows movement of important materials, such as oxygen, around the body.

This circulatory system has two divisions: the cardiovascular system and the lymphatic system. Now, let’s get our blood flowing and focus on the cardiovascular system!

The term “cardiovascular” can be broken down into cardio-, meaning heart, and -vascular, meaning blood vessels. So, the cardiovascular system consists of the heart and blood vessels, which together make up the blood transportation network of the body that carries nutrients, oxygen and waste products to and from cells.

The heart is a muscular organ that lies in the chest, and it pumps blood through the network of blood vessels in the body. It’s composed of four chambers: a right and left atrium, as well as a right and left ventricle.

Next are the blood vessels, which are tube-like structures that carry the blood being pumped by the heart. Arteries are the blood vessels that carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, and veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart.

The blood running through these blood vessels also carry signaling molecules, called hormones, which allow for communication between organs and organ systems.

Lastly, blood helps regulate body temperature. For example, when it's really cold outside, the blood vessels lying close to the skin constrict to reduce blood flow, saving the heat within the body.

Now, there are two main networks, called the pulmonary and systemic circulation, that allow for blood circulation between the heart and the tissues in our body.

In the pulmonary circulation, oxygen-depleted blood from body tissues runs from the right atrium to the right ventricle of the heart into the right and left pulmonary arteries, which carry the blood into the right and left lungs.

This is the one exception where arteries carry oxygen-depleted blood. Here, the blood dumps carbon dioxide and receives fresh oxygen via gas exchange.

Then, the blood runs back through four pulmonary veins to the left atrium, where it passes into the left ventricle. This is the one exception where veins carry oxygen-rich blood.

Now, this is where the systemic circulation begins, pumping oxygen-rich blood into the body’s largest artery, called the aorta. Along its course, the aorta gives off smaller arteries that gradually branch into smaller vessels called arterioles.

Near the body tissues, these arterioles further divide into smaller vessels called capillaries. These capillaries form small networks called capillary beds, in which blood flow is reduced. This reduction in blood flow allows the exchange of gases, nutrients and waste products between the blood and tissues.

Now, after this interchange of substances occurs, the capillaries regroup to form venules, which eventually drain into veins, and eventually into the two largest veins called the superior vena cava and the inferior vena cava, which collect blood from the entire body and empty into the right atrium. And once more, the pulmonary circulation cycle restarts.

Ok, now let’s pause for a second and see if you can identify the chambers of the heart and the course of blood through the pulmonary and systemic circulations.

Key Takeaways

The cardiovascular system is a series of organs that work together to circulate blood throughout the body. It includes the heart, which pumps blood through blood vessels; namely the veins, arteries, and capillaries.

Arteries generally carry oxygen-rich blood away from the heart to supply the body with oxygen and nutrients, whereas veins carry carbon dioxide-rich blood and waste products from other parts of the body back into the heart. The capillaries are tiny vessels that allow nutrients and oxygen from the blood to diffuse into surrounding tissues.

Sources

  1. "Clinically Oriented Anatomy" Lippincott Williams & Wilkins (2013)
  2. "Atlas of Human Anatomy" Saunders/Elsevier (2014)
  3. "Introduction to the Lymphatic System" National Cancer Institute SEER Training Modules