Test precision and accuracy

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Test precision and accuracy

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Pharmacokinetics: Drug absorption and distribution
Pharmacokinetics: Drug metabolism
Pharmacokinetics: Drug elimination and clearance
Pharmacodynamics: Drug-receptor interactions
Sympathetic nervous system
Parasympathetic nervous system
Adrenergic receptors
Cholinergic receptors
Cholinomimetics: Direct agonists
Cholinomimetics: Indirect agonists (anticholinesterases)
Muscarinic antagonists
Opioid agonists, mixed agonist-antagonists and partial agonists
Opioid antagonists
Sympathomimetics: Direct agonists
Nervous system anatomy and physiology
Anatomy and physiology of the eye
Anatomy and physiology of the ear
Neuron action potential
Anatomy and physiology of the female reproductive system
Body fluid compartments
Movement of water between body compartments
Renal clearance
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus saprophyticus
Streptococcus pneumoniae
Streptococcus pyogenes (Group A Strep)
Streptococcus agalactiae (Group B Strep)
Streptococcus viridans
Enterococcus
Clostridium perfringens
Clostridium botulinum (Botulism)
Clostridium difficile (Pseudomembranous colitis)
Clostridium tetani (Tetanus)
Listeria monocytogenes
Bacillus anthracis (Anthrax)
Bacillus cereus (Food poisoning)
Corynebacterium diphtheriae (Diphtheria)
Nocardia
Actinomyces israelii
Escherichia coli
Salmonella (non-typhoidal)
Salmonella typhi (typhoid fever)
Pseudomonas aeruginosa
Enterobacter
Bartonella henselae (Cat-scratch disease and Bacillary angiomatosis)
Klebsiella pneumoniae
Shigella
Proteus mirabilis
Yersinia enterocolitica
Legionella pneumophila (Legionnaires disease and Pontiac fever)
Serratia marcescens
Bacteroides fragilis
Yersinia pestis (Plague)
Helicobacter pylori
Vibrio cholerae (Cholera)
Campylobacter jejuni
Neisseria meningitidis
Neisseria gonorrhoeae
Moraxella catarrhalis
Francisella tularensis (Tularemia)
Bordetella pertussis (Whooping cough)
Brucella
Haemophilus influenzae
Haemophilus ducreyi (Chancroid)
Pasteurella multocida
Mycobacterium tuberculosis (Tuberculosis)
Mycobacterium leprae
Mycoplasma pneumoniae
Chlamydia trachomatis
Chlamydia pneumoniae
Treponema pallidum (Syphilis)
Leptospira
Borrelia burgdorferi (Lyme disease)
Borrelia species (Relapsing fever)
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Coxiella burnetii (Q fever)
Ehrlichia and Anaplasma
Gardnerella vaginalis (Bacterial vaginosis)
Abscesses
Sepsis
Epstein-Barr virus (Infectious mononucleosis)
Herpes simplex virus
Cytomegalovirus
Varicella zoster virus
Human herpesvirus 8 (Kaposi sarcoma)
Human herpesvirus 6 (Roseola)
Adenovirus
Parvovirus B19
Hepatitis D virus
Human papillomavirus
Poxvirus (Smallpox and Molluscum contagiosum)
JC virus (Progressive multifocal leukoencephalopathy)
BK virus (Hemorrhagic cystitis)
Coxsackievirus
Poliovirus
Rhinovirus
Viral hepatitis: Clinical
Influenza virus
Measles virus
Mumps virus
Respiratory syncytial virus
Human parainfluenza viruses
West Nile virus
Dengue virus
Yellow fever virus
Zika virus
Hepatitis C virus
Viral hepatitis: Pathology review
Norovirus
Rotavirus
Coronaviruses
Human T-lymphotropic virus
Ebola virus
Rabies virus
Rubella virus
Eastern and Western equine encephalitis virus
Lymphocytic choriomeningitis virus
Hantavirus
Prions (Spongiform encephalopathy)
Histoplasmosis
Blastomycosis
Coccidioidomycosis and paracoccidioidomycosis
Candida
Aspergillus fumigatus
Cryptococcus neoformans
Mucormycosis
Pneumocystis jirovecii (Pneumocystis pneumonia)
Sporothrix schenckii
Malassezia (Tinea versicolor and Seborrhoeic dermatitis)
Plasmodium species (Malaria)
Babesia
Giardia lamblia
Entamoeba histolytica (Amebiasis)
Cryptosporidium
Acanthamoeba
Toxoplasma gondii (Toxoplasmosis)
Naegleria fowleri (Primary amebic meningoencephalitis)
Trypanosoma cruzi (Chagas disease)
Trypanosoma brucei
Trichomonas vaginalis
Leishmania
Strongyloides stercoralis
Enterobius vermicularis (Pinworm)
Ascaris lumbricoides
Trichinella spiralis
Guinea worm (Dracunculiasis)
Angiostrongylus (Eosinophilic meningitis)
Onchocerca volvulus (River blindness)
Wuchereria bancrofti (Lymphatic filariasis)
Loa loa (Eye worm)
Toxocara canis (Visceral larva migrans)
Ancylostoma duodenale and Necator americanus
Anisakis
Trichuris trichiura (Whipworm)
Diphyllobothrium latum
Echinococcus granulosus (Hydatid disease)
Schistosomes
Clonorchis sinensis
Paragonimus westermani
Sarcoptes scabiei (Scabies)
Pediculus humanus and Phthirus pubis (Lice)
Sensitivity and specificity
Positive and negative predictive value
Test precision and accuracy
Incidence and prevalence
Relative and absolute risk
Odds ratio
Attributable risk (AR)
Mortality rates and case-fatality
DALY and QALY
Direct standardization
Indirect standardization
Ecologic study
Cross sectional study
Case-control study
Cohort study
Randomized control trial
Sample size
Placebo effect and masking
Disease causality
Selection bias
Information bias
Confounding
Interaction
Modes of infectious disease transmission
Outbreak investigations
Disease surveillance
Vaccination and herd immunity
Pelvic inflammatory disease
Breast cancer
DiGeorge syndrome
Ataxia-telangiectasia
HIV (AIDS)
Chronic granulomatous disease

Transcript

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Let’s say you want to figure out if eating more daily servings of vegetables will decrease a person’s body mass index (BMI), which is a number calculated by dividing a person’s weight in kilograms by their height in meters squared.

The first step to figuring this out is to collect data about each person in the study, and this is typically done using some type of measurement tool.

For example, we might use a scale to measure a person’s weight, a measuring rod to measure a person’s height, and design a survey to find out how many daily servings of vegetables a person eats.

Now, it’s important to collect high quality data in a study, which means the information collected in the study should accurately reflect what’s really happening.

For example, if a person eats 5 servings of vegetables per day, the data should reflect that they eat 5 servings, instead of 2 servings.

Data quality is determined by the tools used to collect the information, and ideally, these tools have high validity - or accuracy - and high reliability - or repeatability.

A tool with high validity will provide a measurement that’s very close to the true or known value for the thing being measured.

Let’s say we’re going to measure a woman’s weight using two different scales.

One scale is a family heirloom that was passed down over multiple generations - so it’s pretty old - and the other scale was a gift from your friend who’s a doctor - so it’s really modern and sophisticated.

The old scale provides a measurement of 80 kilograms, and the modern scale provides a very different measurement of 66 kilograms.

In reality, this woman weighs 65 kilograms, so, since the modern scale provides a measurement that is closer to the woman’s true weight, the modern scale has higher validity.

Using tools with high validity is important for getting correct results in descriptive or inferential statistics.

For example, if we used the old scale for all the people in the group with hypertension, but used the new scale for the people in the group without hypertension, then we would think the group with hypertension has a much higher mean body mass index than they really do.

This would lead to an overestimation of the association between body mass index and hypertension.

On the other hand, a tool with high reliability will consistently get the same results, no matter how many times the measurement is repeated.

So, let’s say you measure each person’s weight 3 times in a row on each scale.

On the old scale, the 3 measurements are 80 kilograms, 81 kilograms, and 80 kilograms, and on the modern scale, the 3 measurements are 66 kilograms, 75 kilograms, and 60 kilograms.

Now, even though the modern scale has higher validity, it actually has lower reliability, because the results of the 3 tests were not consistent with each other.

Key Takeaways

In testing and measurement, accuracy and precision are two important concepts of the quality of the test results. Accuracy refers to how close the measured value is to the true value. In other words, it reflects the degree to which a test result is correct or exact. A test can be accurate if it uses a tool with high validity.

Precision, on the other hand, refers to the consistency or reproducibility of the results obtained from a test. It reflects the degree of variation or uncertainty in the results. A precise test uses tools with high reliability.

So, a tool with high validity will get results that are close to the true value, and a tool with high reliability will get results that are consistent no matter how many times the measurement is repeated.