Vascular tumors

Last updated: June 18, 2025

Vascular tumors

ULTIMOS FINALES

ULTIMOS FINALES

Skin anatomy and physiology
Hair, skin and nails
Wound healing
Lichen planus
Skin and soft tissue infections: Clinical
Abscesses
Pemphigus vulgaris
Bullous pemphigoid
Skin cancer
Eczematous rashes: Clinical
Acneiform skin disorders: Pathology review
Vitiligo
Hypopigmentation skin disorders: Clinical
Pigmentation skin disorders: Pathology review
Papulosquamous skin disorders: Clinical
Alopecia: Clinical
Blistering skin disorders: Clinical
Autoimmune bullous skin disorders: Clinical
Benign hyperpigmented skin lesions: Clinical
Skin cancer: Pathology review
Lyme Disease
Skin cancer: Clinical
Borrelia burgdorferi (Lyme disease)
Psoriasis
Seronegative and septic arthritis: Pathology review
Hypersensitivity skin reactions: Clinical
Psoriatic arthritis
Papulosquamous and inflammatory skin disorders: Pathology review
Albinism
Alopecia areata
Epidermolysis bullosa
Urticaria
Hereditary angioedema
Contact dermatitis
Pityriasis rosea
Onychomycosis
Erysipelas
Cellulitis
Folliculitis
Necrotizing fasciitis
Pressure ulcer
Hidradenitis suppurativa
Vesiculobullous and desquamating skin disorders: Pathology review
Dermatomyositis
Myalgias and myositis: Pathology review
Mycobacterium leprae
Bites and stings: Clinical
Type I hypersensitivity
Herpes simplex virus
Varicella zoster virus
Human papillomavirus
Coxsackievirus
Candida
Measles virus
Rubella virus
Parvovirus B19
Human herpesvirus 6 (Roseola)
Vascular tumors
Angiosarcomas
Human herpesvirus 8 (Kaposi sarcoma)
Pediculus humanus and Phthirus pubis (Lice)
Actinic keratosis
Sarcoptes scabiei (Scabies)
Malassezia (Tinea versicolor and Seborrhoeic dermatitis)
Telogen effluvium
Rosacea
Impetigo
Poxvirus (Smallpox and Molluscum contagiosum)
Fibrous, cartilage, and synovial joints
Rheumatoid arthritis
Fibromyalgia
Rheumatoid arthritis and osteoarthritis: Pathology review
Osteoarthritis
Joints of the wrist and hand
Back pain: Pathology review
Lower back pain: Clinical
Rheumatoid arthritis: Clinical
Joint pain: Clinical
Carpal tunnel syndrome
Reactive arthritis
Gout
Ankylosing spondylitis
Septic arthritis
Systemic lupus erythematosus
Lupus nephritis
Systemic lupus erythematosus (SLE): Pathology review
Antiphospholipid syndrome
Thrombosis syndromes (hypercoagulability): Pathology review
Seronegative arthritis: Clinical
Scleroderma: Pathology review
Systemic lupus erythematosus (SLE): Clinical
Non-steroidal anti-inflammatory drugs
Acetaminophen (Paracetamol)
Spondylitis
Spondylosis
Sjogren syndrome: Clinical
Sjogren syndrome
Sjogren syndrome: Pathology review
Raynaud phenomenon
Inflammatory myopathies: Clinical
Limited systemic sclerosis (CREST syndrome)
Scleroderma
Polymyositis
Gout and pseudogout: Pathology review
Rheumatic heart disease
Polymyalgia rheumatica
Osteoporosis
Erythema multiforme

Transcript

Watch video only

Vascular tumors are tumors of the blood vessels, and there actually a lot of different types, so this is just a quick overview of three types of tumors: Kaposi sarcoma, hemangioma, and angiosarcoma. Kaposi sarcoma is a malignant vascular tumor that is linked with an infection of the human herpesvirus 8 (otherwise known as HHV-8). And it’s a cancer of the blood vessel endothelial cells. This virus is thought to get inside of the cells, and cause the cells to replicate uncontrollably. This type of cancer is seen in people who have suppressed immune systems. That’s why it’s one of the common diseases you’re at risk of getting if you have AIDS, and is a complication of organ transplant patients.

The most common symptoms of Kaposi sarcoma affect the skin, causing purple and red lesions. These lesions look somewhat like a bruise, but unlike a bruise they don’t blanch, or turn pale, when pressed. That’s because a Kaposi sarcoma has blood filled blood vessels whereas bruises are caused by blood leaking outside of blood vessels into the skin. Initially these lesions start off flat, but over time they may become raised and more painful. In people who have a compromised immune systems, the disease can also cause lesions in other tissues like the mouth, the nose, the throat, the lymph nodes, the lungs, and the gastrointestinal tract.

You can sometimes treat affected skin by surgically removing it or freezing it using cryotherapy, however treating the disease in immunocompromised patients is a little more difficult. If someone’s immune system is compromised because of drugs such as corticosteroids, it might be necessary to adjust immunosuppressants and allow the immune system to recover. It’s a lot harder to treat the disease in an AIDS patient whose immune system is severely compromised, so antiretroviral therapy is commonly used by patients to restore immunity. Radiation and chemotherapy are also treatment options.

Key Takeaways

Vascular tumors are growths that develop in blood vessels or lymphatic vessels. These tumors can be benign or malignant. The most common types of benign vascular tumors are hemangiomas, which typically form in infancy and childhood and often resolve on their own over time. Malignant vascular tumors include angiosarcomas, which can occur in any part of the body, and Kaposi's sarcoma, which is typically seen in people with weakened immune systems, such as those with HIV/AIDS. Treatment for vascular tumors depends on the type, location, and size of the tumor, as well as the overall health of the individual. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
  4. "Kaposi Sarcoma" Archives of Pathology & Laboratory Medicine (2013)
  5. "Hemangioendothelioma" Seminars in Diagnostic Pathology (2013)
  6. "Angiosarcoma: clinical and imaging features from head to toe" The British Journal of Radiology (2017)