Osmosis video - Acute kidney injury: Clinical

Acute kidney injury (AKI) is a sudden, potentially reversible decline in renal function. AKI results in the accumulation of water, nitrogenous wastes, sodium, and other metabolic wastes in the body, and can also lead to electrolyte imbalances. Common causes include dehydration, sepsis, and some drug therapy.

AKI often presents with reduced urine output, but there can be other signs such as edema, and those associated with the accumulation of metabolic wastes such as anorexia, seizures, and altered mental status. Left untreated, it can lead to chronic kidney disease (CKD)