Sepsis
Videos
Notes
Sepsis
Immune system
Hypersensitivity reactions
Anaphylaxis
Asthma
Food allergy
Type I hypersensitivity
Autoimmune hemolytic anemia
Goodpasture syndrome
Graves disease
Hemolytic disease of the newborn
Myasthenia gravis
Pemphigus vulgaris
Rheumatic heart disease
Type II hypersensitivity
Poststreptococcal glomerulonephritis
Serum sickness
Systemic lupus erythematosus
Type III hypersensitivity
Contact dermatitis
Graft-versus-host disease
Type IV hypersensitivity
Immunodeficiences
Asplenia
Common variable immunodeficiency
Hyperimmunoglobulin E syndrome
IgG subclass deficiency
Isolated primary immunoglobulin M deficiency
Selective immunoglobulin A deficiency
X-linked agammaglobulinemia
Adenosine deaminase deficiency
Ataxia-telangiectasia
Hyper IgM syndrome
Severe combined immunodeficiency
Wiskott-Aldrich syndrome
Complement deficiency
Hereditary angioedema
Cytomegalovirus infection after transplant (NORD)
Post-transplant lymphoproliferative disorders (NORD)
Chediak-Higashi syndrome
Chronic granulomatous disease
Leukocyte adhesion deficiency
Immune system pathology review
Blood transfusion reactions and transplant rejection: Pathology review
Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review
Immunodeficiencies: T-cell and B-cell disorders: Pathology review
Assessments
Sepsis
USMLE® Step 1 questions
0 / 1 complete
High Yield Notes
4 pages
Questions
USMLE® Step 1 style questions USMLE
of complete
External References
First Aid
2022
2021
2020
2019
2018
2017
2016
Arthritis p. 476
septic p. 478
Sepsis
acute tubular necrosis p. 627
ARDS p. NaN
immunodeficient patients p. 116
lymphopenia with p. 431
neutropenia with p. 431
shock with p. 321
Streptococcus agalactiae as cause p. 135
Septicemia
Listeria monocytogenes p. , 137
readmissions with p. 277
Waterhouse-Friderichsen syndrome p. 355
Summary
Sepsis is a potentially life-threatening condition that occurs when an infection spreads through the bloodstream and triggers a widespread immune response. The body's normal immune response to infection can sometimes become overactive, leading to widespread inflammation, which can cause tissue damage and affect organ function.
Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. There may also be symptoms related to a specific infection, such as a cough with pneumonia, or painful urination with a kidney infection. In the very young, old, and people with a weakened immune system, there may be no symptoms of a specific infection and the body temperature may be low or normal rather than high.
Insufficient blood flow may be evident by low blood pressure, high blood lactate, or low urine output. Septic shock is low blood pressure due to sepsis that does not improve after reasonable amounts of intravenous fluids are given. Treatment for sepsis typically involves antibiotics to treat the underlying infection, as well as supportive care to address the symptoms and prevent complications.
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