Osmosis video - Buffering and Henderson-Hasselbalch equation
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Video Summary of Buffering and Henderson-Hasselbalch equation
The Henderson-Hasselbalch equation is a mathematical expression that is used to predict how much of a given acid or base is required to produce a desired pH in a given solution. The equation is named after British chemists Louis Hodgkin and Frederick Gowland Hopkins, who developed it in 1898, and German chemist Wilhelm Hasselbalch, who published it in 1909. The Henderson-Hasselbalch equation can be expressed as follows:
pH = pKa + log [base]/[acid] The pH is the desired pH of the solution, pKa is the dissociation constant of the acid, [base] is the concentration of the base, and [acid] is the concentration of the acid.