Angular Cheilitis · What Is It, Causes, Treatment, and More

• Atopic dermatitis (i.e., eczema)  
• Yeast infections of the mouth, such as oral candidiasis (i.e., thrush) 
• Drooling during sleep 
• Poorly fitting dentures  
• Excess skin sagging on the corners of their mouths (i.e., marionette lines)   
• Babies that use pacifiers, suck their thumbs, or drool   

Anyone can develop angular cheilitis, however it’s more common in the elderly and the young due to increased elasticity of skin and denture or pacifier use, respectively. It will typically present as cracking at the corner of one or both sides of the mouth.  

Angular cheilitis can cause bleeding, blistering, or crusting, especially if a bacterial infection is present. The affected area may become red and may swell, which may worsen when the individual licks their lips. Depending on the underlying cause, the symptoms may last a few days to a few weeks or become a chronic condition.  

Treatment depends on the underlying cause, with the primary goal of keeping the corners of the mouth (i.e., labial commissures) dry and free of saliva to prevent further irritation and infection.  

Regular use of lip balms and moisturizing creams containing petroleum can help keep the area hydrated and reduce cracking; however, products with potential allergens—such as fragrance or lanolin—should generally be avoided. When a bacterial infection is identified, treatment typically includes oral or topical antibiotics. If the infection is fungal in origin, a topical antifungal ointment may be prescribed. Topical steroids may also be used to reduce inflammation and alleviate pain. Additionally, poorly fitting dentures should be adjusted or replaced, and maintaining proper oral hygiene is essential. For individuals with nutritional deficiencies, consuming foods rich in protein, iron, and B vitamins is important for both prevention and healing.