Action potentials in myocytes
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Action potentials in myocytes
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Preguntas
Preguntas del estilo USMLE Step 1
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Resumen
An action potential (AP) is a voltage change that propagates along the membrane of a myocyte (muscle cell) or other cells such as a nerve cell. The AP is generated by the movement of positively charged ions, mainly Na+ and K+, across the plasma membrane. This generates an electrical current that travels down the length of the myocyte.
The AP triggers the release of Ca2+ from intracellular stores, which in turn activates contractile proteins within the myocyte. This ultimately leads to muscle contraction.
Fuentes
- "Medical Physiology" Elsevier (2016)
- "Physiology" Elsevier (2017)
- "Human Anatomy & Physiology" Pearson (2017)
- "Principles of Anatomy and Physiology" Wiley (2014)
- "Sinoatrial node dysfunction induces cardiac arrhythmias in diabetic mice" Cardiovascular Diabetology (2014)
- "How does the shape of the cardiac action potential control calcium signaling and contraction in the heart?" Journal of Molecular and Cellular Cardiology (2010)
- "Ionic events responsible for the cardiac resting and action potential" The American Journal of Cardiology (1982)
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