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Aspergillus fumigatus

Summary of Aspergillus fumigatus
Aspergillus fumigatus is a fungus with septate hyphae that branch at 45°, and conidia in radiating chains at ends of conidiophores. It causes invasive aspergillosis, especially in immunocompromised and those with chronic granulomatous disease. It can also cause aspergillomas in pre-existing lung cavities, especially after tuberculosis (TB) infection. Some species of Aspergillus produce aflatoxins, which are associated with hepatocellular carcinoma. Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity response to Aspergillus that is associated with asthma and cystic fibrosis and causes bronchiectasis and eosinophilia.

Assessments
Aspergillus fumigatus

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High Yield Notes
12 pages
Flashcards

Aspergillus fumigatus

19 flashcards
Questions

USMLE® Step 1 style questions USMLE

4 questions

USMLE® Step 2 style questions USMLE

1 questions
Preview

A 60-year-old man comes to the emergency department because of a cough, shortness of breath, hemoptysis and chest pain for three days. His temperature is 37.5°C (99.5°F) and respiratory rate is 24/min. Laboratory studies show a neutrophil count of 450/µL. He has been self-medicating with amoxicillin and clavulanic acid for the past four days, with no improvement. He was diagnosed with acute leukemia two months ago and is currently following induction chemotherapy treatment. Which of the following is the most likely diagnosis?

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