Sporothrix schenckii

Sporothrix schenckii

IMI

IMI

Lymphatic system anatomy and physiology
Introduction to the immune system
Innate immune system
T-cell development
B-cell development
B-cell activation, differentiation, and contraction
T-cell activation
B- and T-cell memory
Spleen histology
Thymus histology
Lymph node histology
Cytokines
Complement system
MHC class I and MHC class II molecules
VDJ rearrangement
Cell-mediated immunity of CD4 cells
Cell-mediated immunity of natural killer and CD8 cells
Antibody classes
Somatic hypermutation and affinity maturation
X-linked agammaglobulinemia
DiGeorge syndrome
Adenosine deaminase deficiency
Severe combined immunodeficiency
Hyper IgM syndrome
Common variable immunodeficiency
Hyperimmunoglobulin E syndrome
Selective immunoglobulin A deficiency
IgG subclass deficiency
Isolated primary immunoglobulin M deficiency
Ataxia-telangiectasia
Wiskott-Aldrich syndrome
Chediak-Higashi syndrome
Complement deficiency
Hereditary angioedema
Chronic granulomatous disease
Leukocyte adhesion deficiency
Contracting the immune response and peripheral tolerance
Type II hypersensitivity
Type III hypersensitivity
Type IV hypersensitivity
Systemic lupus erythematosus
Serum sickness
Staphylococcus epidermidis
Staphylococcus aureus
Streptococcus pyogenes (Group A Strep)
Cell wall synthesis inhibitors: Penicillins
Cell wall synthesis inhibitors: Cephalosporins
Miscellaneous cell wall synthesis inhibitors
Mechanisms of antibiotic resistance
Clostridium perfringens
Clostridium tetani (Tetanus)
Bacillus anthracis (Anthrax)
Yersinia pestis (Plague)
Francisella tularensis (Tularemia)
Borrelia burgdorferi (Lyme disease)
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Coxiella burnetii (Q fever)
Human papillomavirus
HIV (AIDS)
Borrelia species (Relapsing fever)
Pasteurella multocida
Bacteroides fragilis
Varicella zoster virus
Coxsackievirus
Human herpesvirus 6 (Roseola)
Rubella virus
Measles virus
Parvovirus B19
Human herpesvirus 8 (Kaposi sarcoma)
Viral exanthems of childhood: Pathology review
Nucleoside reverse transcriptase inhibitors (NRTIs)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Protease inhibitors
Herpesvirus medications
Integrase and entry inhibitors
Hepatitis medications
Neuraminidase inhibitors
Sensitivity and specificity
Positive and negative predictive value
Herpes simplex virus
Epstein-Barr virus (Infectious mononucleosis)
Anergy, exhaustion, and clonal deletion
Vaccinations
Type I hypersensitivity
Graft-versus-host disease
Contact dermatitis
Cytomegalovirus infection after transplant (NORD)
Bacterial structure and functions
Nocardia
Actinomyces israelii
Brucella
Mycobacterium leprae
Viral structure and functions
Cytomegalovirus
Poxvirus (Smallpox and Molluscum contagiosum)
Sporothrix schenckii
Candida
Malassezia (Tinea versicolor and Seborrhoeic dermatitis)
Leishmania
Loa loa (Eye worm)
Onchocerca volvulus (River blindness)
Trichinella spiralis
Pediculus humanus and Phthirus pubis (Lice)
Sarcoptes scabiei (Scabies)
Protein synthesis inhibitors: Aminoglycosides
Antimetabolites: Sulfonamides and trimethoprim
Protein synthesis inhibitors: Tetracyclines
Miscellaneous protein synthesis inhibitors
DNA synthesis inhibitors: Metronidazole
DNA synthesis inhibitors: Fluoroquinolones
Azoles
Echinocandins
Folliculitis
Erythema multiforme
Cellulitis
Impetigo
Erysipelas
Necrotizing fasciitis
Onychomycosis
Erythropoietin

Key Takeaways

Sporothrix schenckii is a fungus that can be found in soil as well as in living and decomposing plant material such as peat moss. It is known to cause a skin infection known as sporotrichosis, which is also called rose gardener's disease.

Sporotrichosis typically begins as a small bump or nodule at the site of the skin injury and can then spread to nearby lymph nodes, causing them to become swollen and tender. Over time, the infection can progress and form a chain of nodules along the lymphatic vessels, creating a pattern that is sometimes referred to as "sporotrichoid spread." Sporotrichosis can be more severe in individuals with weakened immune systems, and in rare cases, it can affect the lungs, the bones, and the brain.

Sporotrichosis is diagnosed through history, physical exam, and a culture of the infected tissue or discharge. Treatment may involve antifungal medications, such as itraconazole, and in some cases, surgical removal of the infected tissue may be necessary.