Hypothermia: Clinical sciences

Hypothermia: Clinical sciences

Focused chief complaint

Abdominal pain

Approach to biliary colic: Clinical sciences
Approach to periumbilical and lower abdominal pain: Clinical sciences
Approach to pneumoperitoneum and peritonitis (perforated viscus): Clinical sciences
Approach to postoperative abdominal pain: Clinical sciences
Approach to upper abdominal pain: Clinical sciences
Abdominal aortic aneurysm: Clinical sciences
Acute coronary syndrome: Clinical sciences
Acute mesenteric ischemia: Clinical sciences
Acute pancreatitis: Clinical sciences
Adnexal torsion: Clinical sciences
Alcohol-induced hepatitis: Clinical sciences
Aortic dissection: Clinical sciences
Appendicitis: Clinical sciences
Approach to ascites: Clinical sciences
Cholecystitis: Clinical sciences
Choledocholithiasis and cholangitis: Clinical sciences
Chronic mesenteric ischemia: Clinical sciences
Chronic pancreatitis: Clinical sciences
Colonic volvulus: Clinical sciences
Community-acquired pneumonia: Clinical sciences
Diverticulitis: Clinical sciences
Ectopic pregnancy: Clinical sciences
Endometriosis: Clinical sciences
Gastritis: Clinical sciences
Gastroesophageal reflux disease: Clinical sciences
Hepatitis A and E: Clinical sciences
Hepatitis B: Clinical sciences
Hepatitis C: Clinical sciences
Herpes zoster infection (shingles): Clinical sciences
Ileus: Clinical sciences
Infectious gastroenteritis: Clinical sciences
Inflammatory bowel disease (Crohn disease): Clinical sciences
Inflammatory bowel disease (ulcerative colitis): Clinical sciences
Inguinal hernias: Clinical sciences
Intra-abdominal abscess: Clinical sciences
Irritable bowel syndrome: Clinical sciences
Ischemic colitis: Clinical sciences
Large bowel obstruction: Clinical sciences
Lower urinary tract infection: Clinical sciences
Malaria: Clinical sciences
Nephrolithiasis: Clinical sciences
Paraesophageal and hiatal hernia: Clinical sciences
Peptic ulcer disease: Clinical sciences
Pulmonary embolism: Clinical sciences
Pyelonephritis: Clinical sciences
Rectus sheath hematoma: Clinical sciences
Retroperitoneal hematoma: Clinical sciences
Sickle cell disease: Clinical sciences
Small bowel obstruction: Clinical sciences
Spontaneous bacterial peritonitis: Clinical sciences
Testicular torsion (pediatrics): Clinical sciences

Altered mental status

Approach to altered mental status: Clinical sciences
Acute stroke (ischemic or hemorrhagic) or TIA: Clinical sciences
Alcohol withdrawal: Clinical sciences
Approach to encephalitis: Clinical sciences
Approach to epilepsy: Clinical sciences
Approach to hypercalcemia: Clinical sciences
Approach to hypernatremia: Clinical sciences
Approach to hypocalcemia: Clinical sciences
Approach to hypoglycemia: Clinical sciences
Approach to hyponatremia: Clinical sciences
Approach to hypothyroidism: Clinical sciences
Approach to increased intracranial pressure: Clinical sciences
Approach to mood disorders: Clinical sciences
Approach to schizophrenia spectrum and other psychotic disorders: Clinical sciences
Approach to shock: Clinical sciences
Approach to traumatic brain injury: Clinical sciences
Aspiration pneumonia and pneumonitis: Clinical sciences
Community-acquired pneumonia: Clinical sciences
Delirium: Clinical sciences
Diabetic ketoacidosis: Clinical sciences
Hepatic encephalopathy: Clinical sciences
Hospital-acquired and ventilator-associated pneumonia: Clinical sciences
Hyperosmolar hyperglycemic state: Clinical sciences
Hypothermia: Clinical sciences
Hypovolemic shock: Clinical sciences
Lower urinary tract infection: Clinical sciences
Meningitis and brain abscess: Clinical sciences
Opioid intoxication and overdose: Clinical sciences
Opioid withdrawal syndrome: Clinical sciences
Pyelonephritis: Clinical sciences
Subarachnoid hemorrhage: Clinical sciences
Substance use disorder: Clinical sciences
Uremic encephalopathy: Clinical sciences

Decision-Making Tree

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Hypothermia is defined as a core body temperature of less than 95 degrees Fahrenheit or 35 degrees Celsius. It occurs when your body expends more heat than it creates typically due to prolonged exposure to cold, like getting stuck in a snowstorm or losing heat in homes during the winter. Based on the core temperature, hypothermia is divided into mild, moderate, and severe hypothermia. Regardless of the severity, hypothermia puts the individual at a very high risk of becoming hemodynamically unstable and is life-threatening, so it must be managed promptly.

you should first perform an ABCDE assessment. Acute management should be started immediately to stabilize the patient's airway, breathing, and circulation. Next, obtain IV access and consider starting warmed IV fluids. Next, put your patient on continuous vital sign monitoring, including body temperature, blood pressure, heart rate, and pulse oximetry, as well as cardiac telemetry! Finally, if your patient is in cardiac arrest, manage according to ACLS guidelines.

obtain a focused history and physical examination, as well as a 12-Lead ECG. Your patient will have a history of prolonged cold exposure. History could also reveal risk factors like a history of alcohol use, older age, or that your patient is experiencing homelessness; they may also have severe manifestations of psychiatric conditions, like mania or psychosis.

Physical examination will reveal a core temperature lower than 95 ºF or 35ºC, as well as hyperventilation initially, and may progress to hypoventilation as core temperature continues to decrease. In addition, you may notice shivering, but keep in mind that shivering will eventually stop if exposure to cold continues, and your patient may also develop confusion, lethargy, and reduced responsiveness.

The ECG may reveal sinus tachycardia initially, or progress to sinus bradycardia or a junctional rhythm. Keep in mind that junctional rhythm can be distinguished from a sinus bradycardia by the absence of P waves! Additionally, you might notice Osborn waves, also known as J waves, which refer to positive deflections at the junction between the QRS complex and ST segment! Osborn waves are most noticeable in precordial leads such as V3, V4, V5, and V6, and their height roughly correlates with the severity of hypothermia. In more severe cases, the ECG may even reveal ventricular arrhythmias or even asystole.

Here’s a clinical pearl to keep in mind! If your patient’s vital signs or level of consciousness do not match the degree of hypothermia, consider an underlying medical condition, such as infection, trauma, or metabolic conditions, like hypothyroidism, adrenal insufficiency, and hypoglycemia. For example, your patient might present with decreased responsiveness, hypotension, bradycardia, and mild hypothermia, which refers to a core temperature of 90 to 95ºF or 32 to 35 ºC! In this case, you need to order additional laboratory tests, like a CBC and CMP, to identify an underlying cause.

Ok, so if your patient presents with these signs and symptoms, you can diagnose hypothermia. Now, once you diagnose hypothermia, your next step is to assess the degree of hypothermia by measuring the patient’s core temperature. You should measure the patient’s core temperature using a low-reading thermometer, because standard thermometers cannot accurately measure a core temperature below 95 ºF or 35 ºC. The most accurate location to obtain a core temperature is the lower one-third of the esophagus due to its proximity to the heart. However, this requires the passage of an esophageal probe and may not always be practical, so it’s more common to obtain a core temperature from the bladder and rectum.

if the patient’s core temperature ranges between 90 and 95ºF, or 32 and 35ºC, you can classify it as mild hypothermia, so begin passive external rewarming. This includes removing the patient out of the cold if possible, removing any wet clothing, and covering the patient with a blanket or dry garments. If the patient doesn’t respond to passive external rewarming, consider active external rewarming with warm blankets, heating pads, warm baths, or forced warm air.

Sources

  1. "Wilderness Medical Society Clinical Practice Guidelines for the Out-of-Hospital Evaluation and Treatment of Accidental Hypothermia: 2019 Update" Wilderness & Environmental Medicine (2019)
  2. "Accidental Hypothermia: 2021 Update" International Journal of Environmental Research and Public Health (2022)
  3. "Vital Signs in Accidental Hypothermia" High Altitude Medicine & Biology (2021)
  4. "Extracorporeal membrane oxygenation versus conventional rewarming for severe hypothermia in an urban emergency department" Academic Emergency Medicine (2022)
  5. "Harrison’s Principles of Internal Medicine. 21st Edition. New York, NY. " McGraw Hill Education (2022)