Malingering, factitious disorders and somatoform disorders: Pathology review

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Malingering, factitious disorders and somatoform disorders: Pathology review

BMB2

BMB2

Seizures: Pathology review
Seizures: Clinical
Febrile seizure
Seizures and epilepsy
Early infantile epileptic encephalopathy (NORD)
Nonbenzodiazepine anticonvulsants
Migraine medications
Migraine
Neuron action potential
Resting membrane potential
Concussion and traumatic brain injury
Sleep
Sleep disorders: Clinical
Anticonvulsants and anxiolytics: Barbiturates
Anticonvulsants and anxiolytics: Benzodiazepines
Essential tremor
Malingering, factitious disorders and somatoform disorders: Pathology review
Somatic symptom disorders: Clinical
Somatic symptom disorder
Dissociative disorders
Dissociative disorders: Clinical
Amnesia, dissociative disorders and delirium: Pathology review
Narcolepsy (NORD)
Psychomotor stimulants
Trigeminal neuralgia
Muscle weakness: Clinical
Myalgias and myositis: Pathology review
Fibromyalgia
Diabetic nephropathy
Tricyclic antidepressants
Atypical antidepressants
Medications for neurodegenerative diseases
Toxidromes: Clinical
Body focused repetitive disorders
Headaches: Clinical
Demyelinating disorders: Pathology review
Serotonin and norepinephrine reuptake inhibitors
Erb-Duchenne palsy
Klumpke paralysis
Lead poisoning
Hemolytic-uremic syndrome
Vitamin B12 deficiency
Monoclonal gammopathy of undetermined significance
Charcot-Marie-Tooth disease
Inflammatory myopathies: Clinical
Guillain-Barre syndrome
Amyotrophic lateral sclerosis
Spinal muscular atrophy
Muscular dystrophy
Spinal cord reflexes
Myotonic dystrophy
Memory palaces
Herpes simplex virus
Neuromuscular junction and motor unit
Slow twitch and fast twitch muscle fibers
Muscle contraction
Development of the muscular system
Development of the axial skeleton
Patellar tendon rupture
Achilles tendon rupture
Lower back pain: Clinical
Carpal tunnel syndrome
Radial head subluxation (Nursemaid elbow)
Bell palsy
Headaches: Pathology review
Cluster headache
Tension headache
Epidural hematoma
Traumatic brain injury: Clinical
Intracerebral hemorrhage
Subarachnoid hemorrhage
Subdural hematoma
Traumatic brain injury: Pathology review
Idiopathic intracranial hypertension
Vasculitis
Vasculitis: Clinical
Dementia with Lewy bodies
Spinocerebellar ataxia (NORD)
Amyloidosis
Vascular dementia
Dementia and delirium: Clinical
Frontotemporal dementia
Dementia: Pathology review
Hypokinetic movement disorders: Clinical
Alzheimer disease
Movement disorders: Pathology review
Delirium
Parkinson disease
Hyperkinetic movement disorders: Clinical
Back pain: Pathology review
Stroke: Clinical
Compartment syndrome
Macrocytic anemia: Pathology review
Hypokalemia: Clinical
Hyperkalemia: Clinical
Hypothesis testing: One-tailed and two-tailed tests
Paired t-test
One-way ANOVA
Two-way ANOVA
Type I and type II errors
Two-sample t-test
Correlation
Repeated measures ANOVA
Meningitis, encephalitis and brain abscesses: Clinical
Neonatal meningitis
Central nervous system infections: Pathology review
Neisseria meningitidis
Streptococcus pneumoniae
Listeria monocytogenes
Brain abscess
Clostridium tetani (Tetanus)
Clostridium botulinum (Botulism)
Encephalitis
Eastern and Western equine encephalitis virus
West Nile virus
Zika virus
Rabies virus
Poliovirus
JC virus (Progressive multifocal leukoencephalopathy)
Knowledge Shot: What is acute flaccid myelitis, the polio-like paralyzing disease
Meningitis
Cryptococcus neoformans
Aspergillus fumigatus
Candida
Mucormycosis
Coccidioidomycosis and paracoccidioidomycosis
Blastomycosis
Histoplasmosis
Chi-squared test
Naegleria fowleri (Primary amebic meningoencephalitis)
Angiostrongylus (Eosinophilic meningitis)
Varicella zoster virus
Mycobacterium tuberculosis (Tuberculosis)
Normal pressure hydrocephalus
Prions (Spongiform encephalopathy)
Measles virus
Central nervous system infections: Pathology review
Meningitis, encephalitis and brain abscesses: Clinical
Adult brain tumors
Pediatric brain tumors: Pathology review
Adult brain tumors: Pathology review
Pediatric brain tumors
Brain tumors: Clinical
Multiple sclerosis
Tourette syndrome
Ataxia-telangiectasia
Huntington disease
Opsoclonus myoclonus syndrome (NORD)
Primary ciliary dyskinesia
Brain herniation
Spinal disc herniation
Multiple myeloma

Transcript

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A 5 year old girl named Celia is brought to the emergency department by her mother due to a sudden episode of loss of consciousness.

You decide to run some blood tests, which reveal low glucose levels.

After glucose administration, Celia fully recovers.

You admit her to the hospital to do exhaustive studies to start looking for a cause of her hypoglycemia.

The tests all come back normal, so you decide to discharge Celia.

The next morning, Celia has another unexplained episode of hypoglycemia, so you decide to check her blood insulin levels, which are found high, while her C-peptide levels are slightly low.

Some days later, 32 year old Sofia presents to the emergency department.

Sofia is complaining of severe chest pain that has been going on for the past couple hours, and she is certain that she is having a heart attack.

According to the hospital records, she has presented to the emergency department with similar symptoms 7 times within the past 12 months.

And each time, cardiac evaluation was normal.

Upon examination, both cardiac auscultation and ECG are normal.

Sofia becomes frustrated and storms out of the hospital demanding a second opinion.

Based on the initial presentation, both Celia and Sofia have some form of malingering, factitious, or somatic symptom and related disorders.

What all these have in common is that the affected individual claims to have physical or psychological symptoms that aren’t explained by any known physical or mental disorder.

Okay, starting with malingering, this is when individuals are intentionally faking or exaggerating their symptoms in order to achieve some secondary gain or external goal.

This may include getting money, housing, time off from work, access to medications, or even escaping jail time.

In other words, they’re conscious or aware of their specific motivation.

For your exams, remember that these individuals are typically uncooperative, meaning that they demand an extensive workup, but are not satisfied with negative results and don’t adhere to the diagnostic follow-up or treatment plan.

Another clue is that symptoms stop once they achieve their goal.

On the other hand, in factitious disorder, the individuals are intentionally faking or inducing symptoms, but the goal here is to get the attention and sympathy that is often given to someone who’s sick.

And remember that these individuals are usually unconscious or unaware of their motivation, which means that individuals often don’t even realize why they fabricate their symptoms.

Now, there’s factitious disorder imposed on self, and factitious disorder imposed on another.

In factitious disorder imposed on self, formerly known as Munchausen syndrome, individuals mainly pretend to have physical signs and symptoms of a disease.

This is most common in those with healthcare experience, such as healthcare workers or those somehow related to one, which makes them very knowledgeable about the symptoms they are trying to pass off as real.

And that’s an extremely high yield fact!

For your exams, keep in mind that these individuals typically have a medical record of recurrent hospitalizations, and are overeager to go through invasive interventions, like surgical procedures.

But an important difference with malingering is that, in factitious disorder imposed on self, the pretend symptoms persist even after they get the attention, sympathy, or even medical care.

In contrast, there’s factitious disorder imposed on another, formerly known as Munchausen syndrome by proxy.

In this case, the person deliberately makes a second person ill without that person’s knowledge.

Often, this second person is someone they’re responsible for, like a child, an elder, or even a pet.

Remember that this is considered a type of child or elder abuse.

And if that is suspected, it’s the healthcare provider’s responsibility to contact child or elder protective services.

Oftentimes a social worker should be involved to help decide on the best next steps to ensure the individual’s safety, like separating them from the abuser and helping the family cope.

Now, make sure you don’t confuse this with vulnerable child syndrome, which is when a parent believes that their child is unrealistically prone to getting ill or injured.

For your exams, keep in mind that vulnerable child syndrome classically starts after the child goes through a serious disease or life-threatening event.

And it may lead to repeated absences from school or exaggerated use of healthcare services.

Now, remember that these (pause) are all intentional.

So switching gears, there’s somatic symptom and related disorders, where individuals are unintentionally experiencing symptoms that can’t be explained by any physical or mental disorder.

In other words, affected individuals truly believe their symptoms are real, which are often made worse because they can’t be medically explained or treated.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Excessive Illness Behavior" Psychiatric Care of the Medical Patient (2015)
  4. "Essentials of Psychiatry" Wiley (2006)
  5. "The diagnosis and treatment of Munchausen’s syndrome" General Hospital Psychiatry (2003)
  6. "Kaplan & Sadock's Comprehensive Textbook of Psychiatry" NA (2000)
  7. "Diagnostic and Statistical Manual of Mental Disorders" Amer Psychiatric Pub Incorporated (2000)
  8. "Multisomatoform Disorder" Archives of General Psychiatry (1997)