Oxygen therapy: Nursing pharmacology

Oxygen therapy: Nursing pharmacology

gap test med surg

gap test med surg

Aortic aneurysm: Nursing process (ADPIE)
Coronary artery disease (CAD) and angina pectoris: Nursing process (ADPIE)
Hypertension: Nursing process (ADPIE)
Left-sided heart failure: Nursing process (ADPIE)
Myocardial infarction (MI): Nursing process (ADPIE)
Pericardial effusion and cardiac tamponade: Nursing process (ADPIE)
Rheumatic heart disease: Nursing process (ADPIE)
Antihyperlipidemics - Statins: Nursing pharmacology
Calcium-channel blockers: Nursing pharmacology
Angiotensin II receptor blockers (ARBs): Nursing pharmacology
Angiotensin-converting enzyme (ACE) inhibitors: Nursing pharmacology
Antihyperlipidemics - Miscellaneous: Nursing pharmacology
Diabetes insipidus: Nursing process (ADPIE)
Diabetes mellitus (DM): Nursing process (ADPIE)
Diabetic ketoacidosis (DKA): Nursing process (ADPIE)
Hyperosmolar hyperglycemic state (HHS): Nursing process (ADPIE)
Hyperthyroidism: Nursing process (ADPIE)
Hypothyroidism: Nursing process (ADPIE)
Syndrome of inappropriate antidiuretic hormone (SIADH): Nursing process (ADPIE)
Medications for antidiuretic hormone (ADH) disorders: Nursing pharmacology
Medications for thyroid disorders: Nursing pharmacology
Non-insulin injectable antidiabetic drugs - GLP-1 agonists and amylinomimetics: Nursing pharmacology
Oral antidiabetic medications - Alpha-glucosidase inhibitors: Nursing pharmacology
Oral antidiabetic medications - Biguanides and thiazolidinediones: Nursing pharmacology
Oral antidiabetic medications - DPP-4 inhibitors: Nursing pharmacology
Oral antidiabetic medications - Sulfonylureas and meglitinides: Nursing pharmacology
Oral antidiabetic medications - Sodium-glucose co-transporter-2 (SGLT-2) inhibitors: Nursing pharmacology
Insulin: Nursing pharmacology
Medications for growth hormone disorders: Nursing pharmacology
Epistaxis: Nursing process (ADPIE)
Eye injury: Nursing process (ADPIE)
Glaucoma: Nursing process (ADPIE)
Tonsillitis: Nursing process (ADPIE)
Antiglaucoma medications: Nursing pharmacology
Eye anesthetics: Nursing pharmacology
Mydriatics and cycloplegics: Nursing pharmacology
Ophthalmic anti-inflammatories and anti-infectives: Nursing pharmacology
Appendicitis: Nursing process (ADPIE)
Celiac disease: Nursing process (ADPIE)
Cirrhosis: Nursing process (ADPIE)
Gastroesophageal reflux disease (GERD): Nursing process (ADPIE)
Hiatal hernia: Nursing process (ADPIE)
Pancreatitis: Nursing process (ADPIE)
Peptic ulcer disease (PUD): Nursing process (ADPIE)
Antacids: Nursing pharmacology
Antidiarrheals: Nursing pharmacology
Laxatives: Nursing pharmacology
Weight loss medications: Nursing pharmacology
Antiemetics: Nursing pharmacology
Gallstone-dissolving agents: Nursing pharmacology
Gastric mucosal protective agents: Nursing pharmacology
Antispasmodics (GI): Nursing pharmacology
Histamine H2 antagonists: Nursing pharmacology
Proton pump inhibitors (PPIs): Nursing pharmacology
Treatment for Helicobacter pylori: Nursing pharmacology
Diuretics - Osmotic and carbonic anhydrase inhibitors: Nursing pharmacology
Cholinergic therapy (GU): Nursing pharmacology
Acute kidney injury (AKI): Nursing process (ADPIE)
Benign prostatic hyperplasia (BPH): Nursing process (ADPIE)
Urinary incontinence - Stress: Nursing process (ADPIE)
Urinary tract infections (UTIs): Nursing process (ADPIE)
Hemophilia: Nursing process (ADPIE)
Leukemia: Nursing process (ADPIE)
Sickle cell disease: Nursing process (ADPIE)
Anticoagulants - Heparin: Nursing pharmacology
Antiplatelet agents: Nursing pharmacology
Hemostatics: Nursing pharmacology
Iron preparations: Nursing pharmacology
Thrombolytics: Nursing pharmacology
Antihyperlipidemics - Fibrates: Nursing pharmacology
Blood products: Nursing pharmacology
Antihyperlipidemics - Bile acid sequestrants and cholesterol absorption inhibitors: Nursing pharmacology
Anticoagulants - Direct thrombin and factor Xa inhibitors: Nursing pharmacology
Anaphylaxis: Nursing process (ADPIE)
Lyme disease: Nursing process (ADPIE)
Vaccines: Nursing pharmacology
Immunoglobulins: Nursing pharmacology
Immunosuppressants for autoimmune diseases: Nursing pharmacology
Atopic dermatitis: Nursing process (ADPIE)
Frostbite: Nursing process (ADPIE)
Methicillin-resistant Staphylococcus aureus (MRSA): Nursing process (ADPIE)
Pressure injury: Nursing process (ADPIE)
Debridement agents: Nursing pharmacology
Keratolytics: Nursing pharmacology
Antibiotics - Topical: Nursing pharmacology
Antifungals - Topical: Nursing pharmacology
Corticosteroids - Topical: Nursing pharmacology
Acute compartment syndrome: Nursing process (ADPIE)
Fractures: Nursing process (ADPIE)
Gout: Nursing process (ADPIE)
Musculoskeletal injuries: Nursing process (ADPIE)
Rheumatoid arthritis (RA): Nursing process (ADPIE)
Acetylcholinesterase inhibitors for myasthenia gravis: Nursing pharmacology
Analgesics: Nursing pharmacology
Antiepileptics: Nursing pharmacology
Medications for Alzheimer disease: Nursing pharmacology
Skeletal muscle relaxants: Nursing pharmacology
Medications for migraines: Nursing pharmacology
Meningitis: Nursing process (ADPIE)
Parkinson disease: Nursing process (ADPIE)
Seizure disorder: Nursing process (ADPIE)
Stroke: Nursing process (ADPIE)
Trigeminal neuralgia: Nursing process (ADPIE)
Breast cancer: Nursing process (ADPIE)
Tumor lysis syndrome (TLS): Nursing Process (ADPIE)
Plant extracts for chemotherapy: Nursing pharmacology
Antitumor antibiotics: Nursing pharmacology
Alkylating agents: Nursing pharmacology
Peripheral arterial disease (PAD): Nursing process (ADPIE)
Peripheral venous disease (PVD): Nursing process (ADPIE)
Candidiasis: Nursing process (ADPIE)
Gonorrhea and chlamydia: Nursing process (ADPIE)
Pelvic inflammatory disease (PID): Nursing process (ADPIE)
Asthma: Nursing process (ADPIE)
Bacterial pneumonia: Nursing process (ADPIE)
Carbon monoxide poisoning: Nursing process (ADPIE)
Chronic obstructive pulmonary disease (COPD): Nursing process (ADPIE)
Epiglottitis: Nursing process (ADPIE)
Foreign body aspiration and upper airway obstruction: Nursing process (ADPIE)
Laryngotracheobronchitis (LTB) and croup: Nursing process (ADPIE)
Smoke inhalation injury: Nursing process (ADPIE)
Venous thromboembolism (VTE): Nursing process (ADPIE)
Antihistamines: Nursing pharmacology
Bronchodilators: Nursing pharmacology
Corticosteroids - Inhaled: Nursing pharmacology
Mast cell stabilizers - Inhaled: Nursing pharmacology
Leukotriene modifiers: Nursing pharmacology
Medications to control airway secretions: Nursing pharmacology
Oxygen therapy: Nursing pharmacology

Notes

OXYGEN THERAPY
DRUG NAME
oxygen
CLASS
Medical gas
MECHANISM OF ACTION
Administer supplemental oxygen; restore oxygen saturation; pulmonary vasodilator
INDICATIONS
  • Lung diseases: pneumonia, chronic obstructive pulmonary disease (COPD), sleep apnea
  • Blood problems (e.g., anemia)
  • Heart problems: heart failure
ROUTE(S) OF ADMINISTRATION
  • Nasal cannula
  • Face masks
  • Oxygen tent
  • Oxygen hood
SIDE EFFECTS
  • Suppression of hypoxic respiratory drive
  • Oxygen toxicity: severe coughing, dyspnea, death
CONTRAINDICATIONS AND CAUTIONS
  • Prolonged use
  • Use with caution in clients with COPD and clients who are stable after oxygen therapy
NURSING CONSIDERATIONS: OXYGEN THERAPY
ASSESSMENT AND MONITORING
  • Assess for signs of hypoxia; e.g., confusion, difficulty speaking, tachycardia, dyspnea, pallor, cyanosis, increased rate and depth of respirations, accessory muscle use, SpO2 less than 92%
  • Verify oxygen delivery device, flow rate, humidification, target oxygen saturation
  • Nasal cannula, face mask: ensure proper fit, adjust for comfort
  • Check tubing for twists, kinks, attached to device and oxygen source
  • Monitor response to supplemental oxygen; report worsening oxygenation status
    • Oxygen saturation
    • Vital signs
    • Lung sounds
    • Skin for color changes
    • Level of consciousness
  • Monitor pressure points for skin breakdown; provide skin care, padding as needed
CLIENT EDUCATION
  • Purpose of oxygen therapy
  • Oxygen set-up, pulse oximetry
  • Offer emotional support and reassurance for claustrophobia
  • Home oxygen therapy
    • How to wear the delivery device and operate the machinery
    • Wash nasal cannula in warm soapy water at least once each week; replace it every two to four weeks
    • Supplemental oxygen is a medication; administer their oxygen at the prescribed rate, not to discontinue therapy abruptly
    • Increasing their fluid intake can help reduce dryness of mucous membranes
    • Safety measures
      • Keep the oxygen at least five feet away from any heat source
      • Avoid using equipment that could emit a spark
      • Avoid wearing synthetic clothing due to static electricity
      • Avoid use of flammable liquids
      • No smoking
      • Fire extinguisher readily available
Author: Maria Emfietzoglou, MD
Illustrator: Robyn Hughes, MScBMC

Transcript

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Oxygen therapy is the delivery of supplemental oxygen to treat hypoxia, which is when there is not enough oxygen to meet the needs of the body.

Hypoxia can be caused by various lung diseases that interfere with its ability to properly absorb oxygen, such as pneumonia, chronic pulmonary obstructive disease, or COPD for short, and sleep apnea; as well as blood disorders like various types of anemia, where the red blood cells are not able to carry enough oxygen to meet the body’s demands.

Oxygen also acts as a potent pulmonary vasodilator and thus, it can be helpful in clients with heart problems like heart failure, where the heart has trouble pumping enough blood to meet the body’s demands.

Now, various delivery devices can be applied to administer oxygen therapy. The most common choice is the nasal cannula, which typically is used to deliver oxygen at 1 to 6 liters per minute.

This consists of two prongs that are placed into the nostrils, and a band of tubing wraps around the cheeks and behind the ears to keep it in place. A nasal cannula is easy to apply and is less intrusive, so the client can eat, drink, and talk freely.

Bear in mind that nasal cannulas are not ideal for clients who breathe through their mouths, or those who require high oxygen concentrations. In these cases, the preferred choice is usually a face mask that covers the client’s nose and mouth.

There’s a variety of face masks, ranging from simple ones used to deliver oxygen at 6 to 12 liters per minute, to face masks connected with reservoir bags, used to deliver oxygen at 10 to 15 liters per minute.

These include partial-rebreather masks, which consist of a simple face mask and a bag storing exhaled air and pure oxygen. Every time the client inhales, they breathe in oxygen and exhale air from the bag as well as an amount of room air.

With non-rebreather masks, only oxygen from the bag is breathed in, while exhaled air escapes through holes on the sides of the mask. Venturi masks are another variety and can be used when a precise amount of oxygen needs to be administered.

Compared to nasal cannula, face masks are more complicated, they might be more uncomfortable for the client, and they make it harder to eat, drink, and talk.

In some cases, when the client is comatose or has received sedative drugs, accessory devices can be used along with the nasal cannula or face mask in order to secure an open airway, by keeping the tongue off the back of the throat.

These are flexible tubes that go through the nose and up to the throat, known as nasopharyngeal airways, or into the mouth and back to the throat, called oropharyngeal airways.

Finally, some important devices to administer oxygen therapy include oxygen tents and hoods. An oxygen tent is a bendable clear plastic that’s held over the bed to deliver high concentrations of oxygen, and can be used for both adult and pediatric clients.

On the other hand, an oxygen hood is a clear plastic box or dome that contains warmed and humidified oxygen, and is typically used for infants who are able to breathe on their own but need supplemental oxygen.

Alright, although oxygen therapy should never be denied to a client who needs it, it should be used with caution. When a client is given oxygen therapy, as their condition stabilizes, oxygen concentration should be decreased to achieve an oxygen saturation equal or greater than 94%.

That’s because giving supplemental oxygen for a prolonged period can lead to oxygen toxicity, which can result in detrimental effects to the lungs, causing severe coughing, trouble breathing, and can eventually lead to death.

In addition, giving higher oxygen concentrations for an extended period may lead to pulmonary fibrosis. Finally, for clients with COPD, oxygen should not be used in high concentrations at all because they may lose their hypoxic respiratory drive.

Okay, before administering supplemental oxygen to a client, first assess for signs of hypoxia, such as confusion, difficulty speaking, tachycardia, dyspnea, pallor, or cyanosis.

In addition, they may also have an increased rate and depth of respirations, accessory muscle use, and an SpO2 less than 92%.

Then, verify the correct oxygen delivery device is ordered for the prescribed flow rate, confirm if the oxygen is to be humidified, and note the target oxygen saturation.

Sources

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  3. "Weaning Humidified High Flow Oxygen Therapy among Paediatric Patients: An Integrative Review of Literature. 50:37-45" J Pediatr Nurs (2020)
  4. "High-Flow Nasal Cannula Oxygen Therapy Devices. 64(6):735-742" Respir Care (2019)
  5. "Fundamentals of Nursing. 11th edition. ISBN: 978-0-323-81034-0" Elsevier (2022)
  6. "Oxygen therapeutic agents to target hypoxia in cancer treatment. 53:146-151" Curr Opin Pharmacol (2020)
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  8. "Oxygen therapy for critically Ill and post-operative patients.35(6):928-938" J Anesth (2021)