Video - Polycythemia vera (NORD)

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Video Summary

Polycythemia vera is a bone marrow disorder in which there is an overproduction of blood cells, often caused by a JAK2 mutation within hematopoietic cells in the bone marrow. It can lead to elevated hemoglobin and hematocrit and predispose an individual to develop blood clots. Symptoms may include fatigue, weakness, headaches, dizziness, itching, and abdominal pain. Treatment may include medications to lower blood cell formation, and prevention of blood clots, phlebotomy, and radiation therapy.