Osmosis video - Type IV hypersensitivity
00:00 / 00:00
More Videos
07:05
Isolated primary immunoglobulin M deficiency
07:36
Selective immunoglobulin A deficiency
05:15
X-linked agammaglobulinemia
05:37
Adenosine deaminase deficiency
06:20
Ataxia-telangiectasia
08:03
Hyper IgM syndrome
08:52
Wiskott-Aldrich syndrome
07:21
Complement deficiency
06:57
Chronic granulomatous disease
06:56
Leukocyte adhesion deficiency
05:05
DiGeorge syndrome
07:53
Thymic aplasia
Video Summary of Type IV hypersensitivity
Type IV hypersensitivity is a type of delayed-type immune response, in which the immune system responds to an antigen several hours or days after exposure. It is also known as cell-mediated hypersensitivity because tissue damage involves T cells. This can be via either CD4+ T helper cells, which help coordinate the attack, or CD8+ killer or cytotoxic T cells, which directly destroy host cells. Examples include contact dermatitis, poison ivy, tuberculin skin test, and certain drug reactions, such as allopurinol. Treatment options for Type IV hypersensitivity may include medications like corticosteroids and avoiding exposure to the triggering antigen.