Kernig Sign · What Is It, How It’s Used, and More

Published: Oct 17, 2025
Author: Alyssa Haag, MD
Editor: Ahaana Singh
Editor: Ian Mannarino, MD, MBA
Author: Lahav Constantini, MD
Editor: Kelsey LaFayette, DNP, ARNP, FNP-C
Illustrator: Abbey Richard, MSc
Copyeditor: Joy Mapes
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What is Kernig sign?

Kernig sign is a physical maneuver used to evaluate an individual for a suspected case of meningitis, a condition characterized by inflammation of the membranes that surround the brain and spinal cord, called the meninges. Meningitis is typically caused by a viral infection, but it can also result from bacterial, parasitic, or fungal infections. Common symptoms of meningitis include a stiff neck and back; pain in the back, muscles, or neck; light sensitivity; and constitutional symptoms, such as a fever, nausea, vomiting, and headache. More severe symptoms include confusion and seizures. 

A positive Kernig sign increases the likelihood for an existing meningitis diagnosis, yet a negative sign does not exclude the possibility of meningitis. Therefore, further diagnostic testing, like a lumbar puncture, should be conducted when meningitis is suspected in order to ensure a prompt and accurate diagnosis. 

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How is Kernig sign performed?

Kernig sign is performed with the individual lying on their back with their hips and knees flexed and bent at a 90-degree angle. Next, the clinician will slowly extend, or straighten, one knee at a time. Resistance, pain, or an inability to extend the knee is indicative of a positive Kernig sign. Pain felt during this maneuver is usually experienced in the lower back 

Why does Kernig sign happen?

A positive Kernig sign occurs as a result of the movement of the spinal cord or nerves over the inflamed and hypersensitive meninges. Extension of the leg while performing Kernig sign stretches the hamstring, which places tension on the surrounding tissue near the inflamed spinal canal and meninges. This results in the inability to fully straighten the leg without pain or resistance when the hip is flexed at a 90-degree angle. 

What are the most important facts to know about Kernig’s sign?

Kernig sign is an exam maneuver used to assess suspected meningitis, a condition that causes severe stiffness and inflammation around the brain and spinal cord. The maneuver evaluates meningeal inflammation and stiffness by stretching the hamstring muscle. It is performed with the individual lying on their back with their hips and knees flexed. The clinician then slowly attempts to straighten the leg, and if pain or resistance is elicited, the sign is said to be positive. Further diagnostic testing is required in order to confirm the diagnosis of meningitis and determine its underlying etiology.  

Key Takeaways

Definition 

The Kernig sign is a physical examination maneuver used to assess individuals with suspected meningitis. A positive Kernig sign supports the likelihood of meningitis, whereas a negative sign does not rule it out. 

Method 

- Individual lying on their back with hips and knees flexed and bent at 90-degrees  

- The clinician slowly extends one knee at a time  

- Resistance / pain / inability to extend the knee is indicative of a positive Kernig sign  

Mechanism

- Movement of the spinal cord or nerves over the inflamed and hypersensitive meninges  

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References


Mehndiratta M, Nayak R, Garg H, Kumar M, Pandey S. Appraisal of Kernig's and Brudzinski's sign in meningitis. Ann Indian Acad Neurol. 2012;15(4):287-288. doi:10.4103/0972-2327.104337  


Mount HR, Boyle SD. Aseptic and bacterial meningitis: Evaluation, treatment, and prevention. Am Fam Physician. 2017;96(5):314-322.