Pneumothorax occurs when a defect in the pleura allows air to leak into the pleural space, causing partial or total collapse of the affected lung. In this case, however, the trapped air does not continue to accumulate and is in part able to escape during expiration. As a result, intrapleural pressure does not keep increasing, and the affected lung is allowed to partially expand and fill with oxygen during inspiration.
Depending on the cause, pneumothorax can be classified as spontaneous or traumatic. Spontaneous or simple pneumothorax can be further subdivided into primary spontaneous pneumothorax, in the absence of an underlying lung disease, or secondary spontaneous pneumothorax, if an underlying lung disease is present. On the other hand, traumatic pneumothorax can result from any kind of chest trauma, including iatrogenic pneumothorax, which occurs as a complication of a medical procedure.
Both spontaneous and traumatic pneumothorax can evolve into tension pneumothorax, which is life-threatening and can lead to significant respiratory distress and hemodynamic instability. In tension pneumothorax, the pleural injury acts as a one-way valve through which air can enter the pleural space during inspiration but is unable to escape during expiration. With each inhalation, more air gets trapped inside the chest, leaving less space for the lungs to expand.