Accurate dosing is key in oncology nursing. How many tablets should be given to this patient? Do you know the answer? Let’s find out!
The oncology nurse is caring for a patient diagnosed with chronic myelocytic leukemia (CML) prescribed hydroxyurea 15 mg/kg/day.
The medication is available in 400 mg tablets. The patient has lost a significant amount of weight since their initial diagnosis.
The nurse notes that the patient’s prescription from six months ago was 1800 mg per day. The patient’s current weight from the visit today is 176 lbs.
How many tablet(s) should the nurse administer based on the patient’s current weight?
- Round to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.
- Any rounding should be completed at the end of the calculation.
- The answer must be numeric only. Do not add any units of measurement.
Scroll down for the answer!

Want to learn more about this topic?
Watch the Osmosis video: Antimetabolites: Nursing pharmacology
Key Takeaways
- Dosing in oncology is often weight-based for accuracy.
- Patient weight changes require recalculating medication doses.
- Medication rounding should happen at the end of calculations.
- Hydroxyurea tablets come in fixed strengths for dosing flexibility.
- Precise dosing helps ensure safe and effective cancer treatment.

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