Parkinson's disease is a neurodegenerative disorder in which there is progressive depletion of dopaminergic neurons in the basal ganglia, especially in the substantia nigra. Anti-parkinson medications are drugs used in the management of this disorder.
There are a few different classes of medications used to manage Parkinson's Disease. These include dopamine precursors such as levodopa (L-Dopa); dopaminergic drugs such as bromocriptine that increases the amount of dopamine in the brain; monoamine oxidase (MAO)-B inhibitors like rasagiline that blocks an enzyme that breaks down dopamine; and catechol-O-methyltransferase (COMT) inhibitors such as tolcapone which work by stopping an enzyme from breaking down levodopa.
- "Katzung & Trevor's Pharmacology Examination and Board Review,12th Edition" McGraw-Hill Education / Medical (2018)
- "Rang and Dale's Pharmacology" Elsevier (2019)
- "Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition" McGraw-Hill Education / Medical (2017)
- "The history of dopamine and levodopa in the treatment of Parkinson's disease" Movement Disorders (2008)
- "Drugs for Parkinson's disease" Treat Guidel Med Lett (2013)
- "The role of extended-release amantadine for the treatment of dyskinesia in Parkinson's disease patients" Neurodegener Dis Manag (2018)