Breast abscess: Clinical sciences

Last updated: January 30, 2025

Breast abscess: Clinical sciences

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Development of the reproductive system
Anatomy and physiology of the male reproductive system
Anatomy of the male reproductive organs of the pelvis
Anatomy of the male urogenital triangle
Precocious and delayed puberty: Clinical
Delayed puberty
Testicular cancer
Testicular tumors: Pathology review
Menstrual cycle
Gardnerella vaginalis (Bacterial vaginosis)
Pelvic inflammatory disease
Vaginal and vulvar disorders: Pathology review
Human papillomavirus
Breast cancer
Fibrocystic breast changes
Intraductal papilloma
Mastitis
Paget disease of the breast
Cervix and vagina histology
Fallopian tube and uterus histology
Mammary gland histology
Ovary histology
Penis histology
Prostate gland histology
Testis, ductus deferens, and seminal vesicle histology
Amenorrhea
Intrauterine growth restriction
Polyhydramnios
Oligohydramnios
Potter sequence
Urethritis
Ectopic pregnancy
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Gestational trophoblastic disease
Ovarian germ cell tumors
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Polycystic ovary syndrome
Ovarian sex-cord stromal tumors
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Premature ovarian failure
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Chorioamnionitis
Female sexual interest and arousal disorder
Orgasmic dysfunction
Genito-pelvic pain and penetration disorder
Cervical cancer
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Uterine fibroid
Endometritis
Endometrial hyperplasia
Choriocarcinoma
Precocious puberty
5-alpha-reductase deficiency
Kallmann syndrome
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Penile cancer
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Hypospadias and epispadias
Benign prostatic hyperplasia
Prostatitis
Prostate cancer
Erectile dysfunction
Male hypoactive sexual desire disorder
Cryptorchidism
Inguinal hernia
Varicocele
Testicular torsion
Orchitis
Epididymitis
Amenorrhea: Pathology review
Benign breast conditions: Pathology review
Breast cancer: Pathology review
Cervical cancer: Pathology review
Complications during pregnancy: Pathology review
Congenital TORCH infections: Pathology review
Disorders of sex chromosomes: Pathology review
Disorders of sexual development and sex hormones: Pathology review
HIV and AIDS: Pathology review
Ovarian cysts and tumors: Pathology review
Penile conditions: Pathology review
Prostate disorders and cancer: Pathology review
Sexually transmitted infections: Vaginitis and cervicitis: Pathology review
Sexually transmitted infections: Warts and ulcers: Pathology review
Testicular and scrotal conditions: Pathology review
Uterine disorders: Pathology review
Androgens and antiandrogens
Aromatase inhibitors
Estrogens and antiestrogens
Progestins and antiprogestins
Uterine stimulants and relaxants
Adrenergic antagonists: Alpha blockers
PDE5 inhibitors
Estrogen and progesterone
Anatomy and physiology of the female reproductive system
Menopause
Puberty and Tanner staging
Breastfeeding
Oxytocin and prolactin
Testosterone
Pregnancy
Stages of labor
Hypertensive disorders of pregnancy: Clinical
Perinatal infections: Clinical
Antepartum hemorrhage: Clinical
Abnormal uterine bleeding: Clinical
Ovarian cysts, cancer, and other adnexal masses: Clinical
Placenta previa
Preeclampsia & eclampsia
Preterm labor
Postpartum hemorrhage
Postpartum hemorrhage: Clinical
Breast abscess: Clinical sciences
Mastitis: Clinical sciences
Anatomy of the breast
Hyperprolactinemia

Decision-Making Tree

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A breast abscess occurs when a bacterial infection forms a collection of purulent fluid, or pus, which leads to the development of a painful mass in the breast tissue. It is most often a complication of mastitis, which involves inflammation and infection of the breast.

Most cases of mastitis are lactational or puerperal, resulting from prolonged milk stasis, engorgement, and the entry of bacteria through breaks in the nipple.

Rarely, mastitis can be non-lactational or non-puerperal, which can be idiopathic, related to malignancy, or due to infection from recent surgery, nipple piercings, tattoos, or other trauma.

A breast abscess is more likely to occur in patients who smoke, have diabetes, or can even be a sign of a more serious pathology like inflammatory breast cancer.

Most cases are usually caused by methicillin-sensitive Staphylococcus aureus, while other bacteria like Streptococci sp., Staphylococcus epidermidis, and methicillin-resistant Staphylococcus aureus or MRSA may also be implicated.

Alright, when assessing a patient who presents with a chief concern suggesting a skin abscess, you should first perform an ABCDE assessment to determine if your patient is unstable or stable. If the patient is unstable, stabilize the airway and breathing first. Next, address circulation by obtaining IV access and initiating IV fluids for resuscitation.

Here’s a clinical pearl! Keep in mind that it’s very rare for breast abscess to be the sole cause of hemodynamic instability. Thus, if the patient is unstable, then they’ve likely developed sepsis or even septic shock.

Okay, now that you have taken care of your unstable patients, let’s talk about stable patients. Your first step is to obtain a focused history and physical examination.

Your patient will usually report breast pain, swelling, and purulent discharge from the nipple or from a lesion on the skin.

Make sure to ask about risk factors like a history of smoking, diabetes, recent childbirth, and if they are currently breastfeeding.

When it comes to the physical exam, it might reveal increased warmth over the affected area, as well as erythema, and possible edema. Additionally, you might feel a fluctuant, tender, or palpable mass. Patients also often present with fever. If any of these signs and symptoms are present, you are likely dealing with a breast abscess.

Okay, now that the diagnosis is made, let’s talk about the management. This includes empiric antibiotics and pain medications. Penicillinase-resistant penicillins like dicloxacillin, or a first-generation cephalosporin is the antibiotic of choice,

but for patients with beta-lactam hypersensitivity, or if MRSA is suspected, you can use clindamycin instead.

Sources

  1. "Breast infections: A review of current literature" Am J Surg (2024)
  2. "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021" Crit Care Med (2021)
  3. "The Breast" Schwartz’s Principles of Surgery, 10th ed. (2014)
  4. "Treatment of breast infection" BMJ (2011)
  5. "Breast abscesses in lactating women" World J Surg (2003)
  6. "Select Choices in Benign Breast Disease: An Initiative of the American Society of Breast Surgeons for the American Board of Internal Medicine Choosing Wisely® Campaign" Ann Surg Oncol (2018)
  7. "Trends in non-lactation breast abscesses in a tertiary hospital setting" ANZ J Surg (2018)