Skin abscess: Clinical sciences

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Skin abscess: Clinical sciences
Clinical conditions
Abdominal pain
Acid-base
Acute kidney injury
Altered mental status
Anemia: Destruction and sequestration
Anemia: Underproduction
Back pain
Bleeding, bruising, and petechiae
Cancer screening
Chest pain
Constipation
Cough
Diarrhea
Dyspnea
Edema: Ascites
Edema: Lower limb edema
Electrolyte imbalance: Hypocalcemia
Electrolyte imbalance: Hypercalcemia
Electrolyte imbalance: Hypokalemia
Electrolyte imbalance: Hyperkalemia
Electrolyte imbalance: Hyponatremia
Electrolyte imbalance: Hypernatremia
Fatigue
Fever
Gastrointestinal bleed: Hematochezia
Gastrointestinal bleed: Melena and hematemesis
Headache
Jaundice: Conjugated
Jaundice: Unconjugated
Joint pain
Knee pain
Lymphadenopathy
Nosocomial infections
Skin and soft tissue infections
Skin lesions
Syncope
Unintentional weight loss
Vomiting
Assessments
USMLE® Step 2 questions
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Decision-Making Tree
Questions
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Transcript
A skin abscess is a common skin and soft tissue infection that occurs when a collection of pus accumulates, usually in the dermis or subcutaneous space. An abscess can result from a disruption in the skin barrier or prior skin infection, which allows the bacteria to get into the subcutaneous space. The most common cause of a skin abscess is bacteria, especially Staphylococcus aureus, either methicillin-susceptible or methicillin-resistant. When it comes to presentation, a skin abscess can present with or without systemic symptoms.
Alright, when assessing a patient who presents with signs and symptoms suggestive of a skin abscess, you should first perform an ABCDE assessment to determine if your patient is unstable or stable. If the patient is unstable, stabilize the airway, breathing, and circulation first. Next, obtain IV access and initiate IV fluids for resuscitation.
Here’s a clinical pearl! Keep in mind that most patients with skin abscesses wouldn't be unstable, and if they are unstable, then they’ve likely developed sepsis or even septic shock. So be sure to evaluate these patients for systemic signs and symptoms like hypotension, fever, and chills.
Now that acute management for unstable patients is initiated, let’s talk about stable patients. If the patient is stable, your first step is to obtain a focused history and physical examination, evaluating the affected area while also looking for associated systemic signs and symptoms like fevers or chills; along with labs like CBC.
Let’s first look at a patient without systemic signs and symptoms. Your patient might report a small painful, erythematous nodule, with or without spontaneous drainage. On a physical exam, you might see a fluctuant nodule with or without erythema and tenderness. Finally, labs might be normal or show mild leukocytosis. In this case, you can diagnose a skin abscess. Now, since the patient doesn’t have any systemic signs or symptoms, we can refer to it as an abscess without systemic signs and symptoms.
Okay, now that you have made the diagnosis, the next step is to proceed with a surgical consultation for simple incision and drainage with daily dressing changes.
Once the abscess has been drained, you should wait for 24 to 48 hours to assess the response to treatment. Logically, if the abscess is gone, no further treatment is needed, but remember that dressings will need to be changed daily until the abscess cavity resolves too. Now, in some cases, the abscess might reaccumulate in those 24 to 48 hours. This means that the patient has a refractory abscess secondary to loculations or inadequate drainage procedure. If this is the case, you should consider repeating the incision and drainage, performing debridement, or adding an antibiotic that would cover skin flora, like trimethoprim-sulfamethoxazole, or a first generation cephalosporin such as cephalexin..
Sources
- "Executive Summary: Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America" Clinical Infectious Diseases (2014)
- "Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors" Clin Infect Dis (2016)
- "Eschar with Cellulitis as a Clinical Predictor in Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Skin Abscess" The Journal of Emergency Medicine (2010)
- "Cellulitis: current insights into pathophysiology and clinical management" Neth J Med (2017)
- "Route and duration of antibiotic therapy in acute cellulitis: A systematic review and meta-analysis of the effectiveness and harms of antibiotic treatment" J Infect (2020)
- "Interventions for the prevention of recurrent erysipelas and cellulitis" Cochrane Database Syst Rev (2017)
- "National Trends in Incidence of Purulent Skin and Soft Tissue Infections in Patients Presenting to Ambulatory and Emergency Department Settings, 2000-2015" Clin Infect Dis (2020)
- "Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children" Clin Infect Dis (2011)
- "Incidence of skin and soft tissue infections in ambulatory and inpatient settings, 2005-2010" BMC Infect Dis (2015)
- "Cellulitis: A Review" JAMA (2016)
- "Clinical practice. Cellulitis" N Engl J Med (2004)
- "Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality" Crit Care Med (2011)