Bullous pemphigoid
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Summary of Bullous pemphigoid
Bullous pemphigoid
Bullous pemphigoid is an acute or chronic autoimmune skin disease, involving the formation of thick-walled blisters, more appropriately known as bullae, at the space between the epidermis and dermis. It is classified as a type II hypersensitivity reaction, with the formation of anti-hemidesmosome antibodies.
Flashcards on Bullous pemphigoid
Bullous pemphigoid
11 flashcards
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Bullous pemphigoid is a skin disorder characterized by (cell-cell adhesion structure) destruction along the dermal-epidermal junction.
Questions on Bullous pemphigoid
Bullous pemphigoid
USMLE® Step 1 style questions
5 questions
Bullous pemphigoid
USMLE® Step 2 style questions
5 questions
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A 35-year-old man comes to the clinic because of painful severe blistering over his buttocks for the past week. About a year ago, he noticed a similar outbreak on his inner thighs, but it receded within a few days on its own. Physical examination shows that blisters are tense, and rubbing the affected skin does not result in “popping” of the blisters. A biopsy, shown below, shows extensive inflammatory infiltrates abundant with eosinophils. Which of the following cellular structures, if defective, is most likely involved in the formation of these blisters?