Hemothorax: Clinical sciences

Last updated: January 30, 2025

Hemothorax: Clinical sciences

CCRN Prep Total

CCRN Prep Total

Anatomic and physiologic dead space
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Gas exchange in the lungs, blood and tissues
Approach to a cough (pediatrics): Clinical sciences
Reading a chest X-ray
Approach to respiratory distress (newborn): Clinical sciences
Approach to chest pain: Clinical sciences
Acute respiratory distress syndrome
Respiratory distress syndrome: Pathology review
Respiratory failure (pediatrics): Clinical sciences
Acute respiratory distress syndrome: Clinical sciences
Approach to postoperative respiratory distress: Clinical sciences
Approach to dyspnea: Clinical sciences
Upper respiratory tract infection
Apnea of prematurity
Approach to complications of prematurity (early): Clinical sciences
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Hospital-acquired and ventilator-associated pneumonia: Clinical sciences
Acid-base map and compensatory mechanisms
Respiratory acidosis
Approach to respiratory alkalosis: Clinical sciences
Approach to lower airway obstruction (pediatrics): Clinical sciences
Approach to upper airway obstruction (pediatrics): Clinical sciences
Croup and epiglottitis: Clinical sciences
Croup
Pharyngitis, peritonsillar abscess, and retropharyngeal abscess (pediatrics): Clinical sciences
Asthma: Clinical sciences
Bronchodilators: Beta 2-agonists and muscarinic antagonists
Pneumonia: Pathology review
Pneumothorax
Pneumothorax: Clinical sciences
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Atelectasis: Clinical sciences
Approach to penetrating chest injury: Clinical sciences
Pulmonary embolism
Pulmonary embolism: Clinical sciences
Pulmonary shunts
Pulmonary hypertension
Pulmonary hypertension: Clinical sciences
Hypertension
Hypertensive emergency
Hypertension: Pathology review
Tracheoesophageal fistula
Esophageal atresia and tracheoesophageal fistula: Year of the Zebra
Bronchiolitis: Clinical sciences
Blood transfusion reactions and transplant rejection: Pathology review
Spinal fractures: Clinical sciences
Anatomy of the descending spinal cord pathways
Approach to differentiating lesions (spinal cord): Clinical sciences
Brain death: Clinical sciences
Pneumonia (pediatrics): Clinical sciences
Brain herniation
Pediatric brain tumors
Delirium
Delirium: Clinical sciences
Approach to encephalopathy (acute and subacute): Clinical sciences
Encephalitis
Approach to altered mental status: Clinical sciences
Approach to traumatic brain injury: Clinical sciences
Approach to traumatic brain injury (pediatrics): Clinical sciences
Traumatic brain injury: Pathology review
Epidural hematoma
Approach to trauma (pediatrics): Clinical sciences
Concussion and traumatic brain injury
Subarachnoid hemorrhage: Clinical sciences
Normal pressure hydrocephalus
Intracerebral hemorrhage
Approach to increased intracranial pressure: Clinical sciences
Subarachnoid hemorrhage
Neurogenic shock: Clinical sciences
Approach to shock (pediatrics): Clinical sciences
Shock: Pathology review
Shock
Approach to shock: Clinical sciences
Ischemic stroke
Acute stroke (ischemic or hemorrhagic) or TIA: Clinical sciences
Cerebral vascular disease: Pathology review
Arteriovenous malformation
Meningitis
Pelvic fractures: Clinical sciences
Subdural hematoma
Community-acquired pneumonia: Clinical sciences
Meningitis (pediatrics): Clinical sciences
Meningitis and brain abscess: Clinical sciences
Central nervous system infections: Pathology review
Syndrome of inappropriate antidiuretic hormone secretion: Clinical sciences
Approach to convulsive status epilepticus: Clinical sciences
Seizures and epilepsy
Approach to epilepsy: Clinical sciences
Approach to altered mental status (pediatrics): Clinical sciences
Nonbenzodiazepine anticonvulsants
Seizures: Pathology review
Spina bifida
Congenital neurological disorders: Pathology review
Electrolyte disturbances: Pathology review
Hyperosmolar hyperglycemic state: Clinical sciences
Compartment syndrome: Clinical sciences
Renal system anatomy and physiology
Intrinsic acute kidney injury (glomerular causes): Clinical sciences
Prerenal acute kidney injury: Clinical sciences
Prerenal azotemia
Intrinsic acute kidney injury (non-glomerular causes): Clinical sciences
Postrenal acute kidney injury: Clinical sciences
Approach to acute kidney injury: Clinical sciences
Approach to postoperative acute kidney injury: Clinical sciences
Renal failure: Pathology review
Chronic kidney disease
Chronic kidney disease: Clinical sciences
Nephrotic syndromes: Pathology review
Approach to hyperkalemia: Clinical sciences
Transplant rejection
Nephritic syndromes (pediatrics): Clinical sciences
The role of the kidney in acid-base balance
Urinary tract infections and kidney stones in pregnancy: Clinical sciences
Hemolytic-uremic syndrome
Approach to bleeding disorders (thrombocytopenia): Clinical sciences
Extrinsic hemolytic normocytic anemia: Pathology review
Thrombotic microangiopathy: Clinical sciences
Platelet disorders: Pathology review
Approach to blunt and penetrating abdominal injury: Clinical sciences
Approach to postoperative abdominal pain: Clinical sciences
Approach to acute abdominal pain (pediatrics): Clinical sciences
Non-accidental trauma and neglect (pediatrics): Clinical sciences
Small bowel ischemia and infarction
Bowel obstruction
Large bowel obstruction: Clinical sciences
Small bowel obstruction: Clinical sciences
Short bowel syndrome: Clinical sciences
Gastrointestinal bleeding: Pathology review
Hypovolemic shock: Clinical sciences
Congenital gastrointestinal disorders: Pathology review
Approach to bleeding disorders (platelet dysfunction): Clinical sciences
Cholestatic liver disease
Non-alcoholic fatty liver disease
Post-transplant lymphoproliferative disorders (NORD)
Transposition of the great vessels
Intussusception
Intussusception: Clinical sciences
Approach to the acute abdomen (pediatrics): Clinical sciences
Vasculitis: Pathology review
Necrotizing enterocolitis: Clinical sciences
Necrotizing enterocolitis: Year of the Zebra 2024
Guillain-Barré syndrome: Clinical sciences
Disseminated intravascular coagulation: Clinical sciences
Disseminated intravascular coagulation
Consumptive coagulopathy from massive transfusion: Clinical sciences
Sepsis: Clinical sciences
Approach to leukemia: Clinical sciences
Thrombosis syndromes (hypercoagulability): Pathology review
Malignant hyperthermia: Clinical sciences
Acute pancreatitis
Adrenal insufficiency: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Immune thrombocytopenia
Immune thrombocytopenia: Clinical sciences
Hematopoietic medications
Glucocorticoids
Sickle cell disease: Clinical sciences
Anatomy clinical correlates: Spinal cord pathways
Acute coronary syndrome: Clinical sciences
Antidiuretic hormone
Diabetes insipidus and SIADH: Pathology review
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Hyponatremia
Approach to hyponatremia: Clinical sciences
Approach to hyponatremia (pediatrics): Clinical sciences
Diabetes insipidus
Diabetes insipidus: Clinical sciences
Approach to hypoglycemia: Clinical sciences
Approach to hypoglycemia (pediatrics): Clinical sciences
Diabetic ketoacidosis: Clinical sciences
Diabetes mellitus (pediatrics): Clinical sciences
Diabetes mellitus: Pathology review
Pulmonary edema
Cerebral palsy
Hepatic encephalopathy: Clinical sciences
Approach to common musculoskeletal injuries (pediatrics): Clinical sciences
Approach to blunt chest injury: Clinical sciences
Pediatric musculoskeletal disorders: Pathology review
Approach to extremity injury: Clinical sciences
Neuroblastoma
Childhood and early-onset psychological disorders: Pathology review
Approach to trauma: Clinical sciences
Anatomy clinical correlates: Skull, face and scalp
Rhabdomyolysis
Compartment syndrome
Hypocalcemia
Hyperphosphatemia
Hyperkalemia
Sepsis (pediatrics): Clinical sciences
Sepsis
Neonatal sepsis
Empyema: Clinical sciences
Necrotizing soft tissue infections: Clinical sciences
Pressure-induced skin and soft tissue injury: Clinical sciences
Diffusion-limited and perfusion-limited gas exchange
Approach to acid-base disorders: Clinical sciences
Definitions of acids and bases
Acid-base disturbances: Pathology review
Catheter-associated urinary tract infection: Clinical sciences
Central line-associated bloodstream infection: Clinical sciences
Approach to medication exposure (pediatrics): Clinical sciences
Approach to household substance exposure (pediatrics): Clinical sciences
Approach to recreational substance exposure (pediatrics): Clinical sciences
Myocarditis: Clinical sciences
Pharmacodynamics: Drug-receptor interactions
Medication overdoses and toxicities: Pathology review
Opioid intoxication and overdose: Clinical sciences
Approach to stimulant use, intoxication, and overdose: Clinical sciences
Approach to hallucinogen, inhalant, and cannabis use, intoxication, and overdose: Clinical sciences
Cholinomimetics: Indirect agonists (anticholinesterases)
Suicide
Burns
Burns: Clinical sciences
Multiple organ dysfunction syndrome (MODS): Clinical sciences
Kawasaki disease
Approach to hypernatremia (pediatrics): Clinical sciences
Approach to a postoperative fever: Clinical sciences
Supraventricular arrhythmias: Pathology review
Aspiration pneumonia and pneumonitis: Clinical sciences
Cardiac preload
Cardiac cycle
Cardiac tumors
Cardiac work
Cardiac tamponade
Cardiac tamponade: Clinical sciences
Cardiac conduction velocity
Cardiac afterload
Cardiac contractility
ECG cardiac hypertrophy and enlargement
Ventricular tachycardia: Clinical sciences
Ventricular arrhythmias: Pathology review
ECG cardiac infarction and ischemia
Approach to tachycardia: Clinical sciences
Stroke volume, ejection fraction, and cardiac output
Dilated cardiomyopathy
Supraventricular tachycardia: Clinical sciences
Class IV antiarrhythmics: Calcium channel blockers and others
Atrial fibrillation and atrial flutter: Clinical sciences
Positive inotropic medications
Class I antiarrhythmics: Sodium channel blockers
Cardiomyopathies: Pathology review
Class III antiarrhythmics: Potassium channel blockers
Hypertrophic cardiomyopathy
Ventricular fibrillation
Aortic stenosis: Clinical sciences
Myocarditis
Brief, resolved, unexplained event (BRUE): Clinical sciences
Mitral stenosis: Clinical sciences
Congestive heart failure: Clinical sciences
Atrial flutter
Pressures in the cardiovascular system
Cardiovascular system anatomy and physiology
Restrictive cardiomyopathy
Airflow, pressure, and resistance
Total anomalous pulmonary venous return
Atrial fibrillation
Hypertrophic cardiomyopathy: Clinical sciences
Hypothermia: Clinical sciences
Hemothorax: Clinical sciences
Anaphylaxis: Clinical sciences
Abdominal aortic aneurysm: Clinical sciences
Muscarinic antagonists
Selective serotonin reuptake inhibitors
General anesthetics
Neuromuscular blockers
Right heart failure: Clinical sciences
Heart failure: Pathology review
Mitral valve disease
Approach to a murmur (pediatrics): Clinical sciences
Tricuspid valve disease
ACE inhibitors, ARBs and direct renin inhibitors
Patent ductus arteriosus
Adrenergic antagonists: Beta blockers
Pheochromocytoma
cGMP mediated smooth muscle vasodilators
Cardiac conduction system
Hypoplastic left heart syndrome
Hypoplastic left heart syndrome: Year of the Zebra 2024
Heart blocks: Pathology review
Rheumatic heart disease
Abnormal heart sounds
Valvular heart disease: Pathology review
Coronary artery disease: Pathology review
Pericarditis: Clinical sciences
Approach to hypertension: Clinical sciences
Deep vein thrombosis
Deep vein thrombosis: Clinical sciences
Approach to a fever: Clinical sciences
Anticoagulants: Heparin
Approach to hypercoagulable disorders: Clinical sciences
Heparin-induced thrombocytopenia
Thrombolytics
Atrial septal defect
Superior vena cava syndrome
Introduction to the somatic and autonomic nervous systems
Anticonvulsants and anxiolytics: Benzodiazepines
Anticonvulsants and anxiolytics: Barbiturates
Approach to congenital heart diseases (acyanotic): Clinical sciences
Tetralogy of Fallot
Cyanotic congenital heart defects: Pathology review
Approach to congenital heart diseases (cyanotic): Clinical sciences
Ventricular septal defect
Aortic valve disease
Pyloric stenosis
Aortic dissection
Pneumonia
Aortic dissection: Clinical sciences
Aortic dissections and aneurysms: Pathology review
Coarctation of the aorta
Acyanotic congenital heart defects: Pathology review
Pulmonary valve disease
Pulmonary chemoreceptors and mechanoreceptors
Zones of pulmonary blood flow
Carotid artery stenosis screening: Clinical sciences
Endocarditis
Endocarditis: Pathology review
Valvular insufficiency (regurgitation): Clinical sciences
Infectious endocarditis: Clinical sciences
Choanal atresia
Tetralogy of Fallot: Year of the Zebra
Mycoplasma pneumoniae
Measles virus
Respiratory alkalosis
Metabolic alkalosis
Approach to metabolic alkalosis: Clinical sciences
Approach to respiratory acidosis: Clinical sciences
Metabolic acidosis
Approach to metabolic acidosis: Clinical sciences
Pericardial disease: Pathology review
Atherosclerosis and arteriosclerosis: Pathology review
Cardiac and vascular tumors: Pathology review
Peripheral artery disease: Pathology review

Decision-Making Tree

Transcript

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A hemothorax is the collection of blood within the chest cavity, or the pleural space to be more specific. This collection can be a result of direct trauma to the chest, or can occur spontaneously when patients have pre-existing clotting disorders. It’s important to address the hemothorax in a timely manner to acutely avoid a potentially life-threatening hemorrhage, as well as to avoid chronically the formation of a fibrothorax, which is an organized clot within the chest cavity surrounding and restricting the patient’s lung from expanding.

When approaching a patient who presents with signs and symptoms suggestive of a hemothorax, your first step is to do an ABCDE assessment in order to determine if the patient is stable or unstable. If the patient is unstable, you need to secure their airway, obtain IV access, and begin resuscitation, as well as monitor and manage their vital signs. Next, obtain a quick focused history and physical exam. Unstable patients with hemothorax typically present with dyspnea and chest pain.

Additionally, they might have a history of an underlying cause, such as chest trauma or recent chest or cardiac procedures like thoracentesis or coronary angiography, as well as a history of cancer, potentially causing erosion into great vessels; thoracic aortic aneurysm; or prior clotting disorders or coagulopathy. On physical examination, you’ll find these patients to be hypotensive and tachycardic. Now, as one side of the chest is full of blood, that lung will be restricted, so you’ll typically find absent unilateral breath sounds. In addition, since that side has no airflow, you might also notice dullness to percussion and decreased tactile fremitus on the affected side.

Okay, because the patient is unstable, you need to act fast! Start by ordering a chest x-ray, which will reveal fluid within the pleural cavity, and can help you rule out several life-threatening conditions. Another quick and reliable way to get an idea of what’s going on is an E-FAST examination. E-FAST involves performing an ultrasound at the bedside to examine the chest and abdominal cavity for the presence of any unusual fluid collection, which typically means blood. If you see fluid within the pleural cavity, suspect a hemothorax.

If this is the case, the first thing you want to do is drain the blood by placing a large bore chest tube, 32 French or greater to prevent tube clotting. Placing the chest tube and releasing the tension will help stabilize most patients. In addition, depending on the severity of the bleed, some patients may need a transfusion. Lastly, you should get emergent surgical consultation, who will manage resuscitation and decide if surgery is needed, such as to explore the thoracic cavity and look for the source of the bleeding.

Now that unstable patients are taken care of, let’s talk about stable patients. Your first step here is to obtain a focused history and physical examination. Similarly to unstable patients, stable ones typically report dyspnea, chest pain, and possibly a history of chest trauma or clotting problems. When it comes to the physical exam, you can expect to find similar findings as before. So, there could be absent unilateral breath sounds, dullness to percussion, and decreased tactile fremitus on the affected side.

Once you’ve obtained both history and physical examination, you should order labs, including a CBC and INR, as well as a chest x-ray. If the labs and chest x-ray are normal, you should consider an alternative diagnosis. On the other hand, labs that point to hemothorax include a normal WBC count, low hemoglobin, and possible low platelets or elevated INR. If you see these lab findings, combined with a chest x-ray that shows opacification of one hemithorax or blunting of one costophrenic angle, suspect the presence of a hemothorax.

Now, this isn’t really enough to make a diagnosis of hemothorax, so you should confirm it with a CT scan of the chest. The CT may show a heterogeneous collection with areas of increased attenuation within the pleural cavity, which is because both fresh and thicker blood clots can attenuate differently on CT. If the CT is with IV contrast, you may see extravasation. If you see these findings on CT, you have confirmed the diagnosis of a hemothorax.

Okay, once the diagnosis of hemothorax is confirmed, start the treatment right away! As before, start by placing the chest tube to drain the collection. After the chest tube has been placed, obtain a follow-up chest x-ray to see if the hemothorax has resolved.

Sources

  1. "Hemothorax" Thoracic Surgery Clinics (2013)
  2. "Scoping review of traumatic hemothorax: Evidence and knowledge gaps, from diagnosis to chest tube removal" Surgery (2021)
  3. "Practice Management Guidelines for Management of Hemothorax and Occult Pneumothorax" Journal of Trauma: Injury, Infection & Critical Care (2011)
  4. "Management of simple and retained hemothorax: A practice management guideline from the Eastern Association for the Surgery of Trauma" The American Journal of Surgery (2021)
  5. "Etiology and management of spontaneous haemothorax" J thoracic dis (2015)
  6. "Hemothorax: A Review of the Literature" Clin pulm med (2020)