Skeletal system anatomy and physiology

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Skeletal system anatomy and physiology

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Cardiovascular system anatomy and physiology
Normal heart sounds
Abnormal heart sounds
Blood pressure, blood flow, and resistance
Measuring cardiac output (Fick principle)
Pressures in the cardiovascular system
Baroreceptors
Chemoreceptors
Renin-angiotensin-aldosterone system
Cardiac contractility
Cardiac conduction system
Myocardial infarction
Angina pectoris
Aortic dissection
Aneurysms
Tricuspid valve disease
Mitral valve disease
Pulmonary valve disease
Aortic valve disease
Hypertrophic cardiomyopathy
Skin anatomy and physiology
Wound healing
Hair, skin and nails
Atopic dermatitis
Psoriasis
Lichen planus
Albinism
Burns
Actinic keratosis
Skin cancer
Endocrine system anatomy and physiology
Thyroid hormones
Cortisol
Synthesis of adrenocortical hormones
Calcitonin
Parathyroid hormone
Vitamin D
Cushing syndrome
Diabetes mellitus
Hyperparathyroidism
Hypoparathyroidism
Hypothyroidism
Hyperthyroidism
Toxic multinodular goiter
Graves disease
Thyroid cancer
Pheochromocytoma
Neuroblastoma
Gastrointestinal system anatomy and physiology
Pancreatic secretion
Liver anatomy and physiology
Bile secretion and enterohepatic circulation
Carbohydrates and sugars
Proteins
Fats and lipids
Prebiotics and probiotics
Vitamins and minerals
Barrett esophagus
Mallory-Weiss syndrome
Gastroesophageal reflux disease (GERD)
Boerhaave syndrome
Peptic ulcer
Gastritis
Colorectal polyps
Ulcerative colitis
Gallstones
Cirrhosis
Non-alcoholic fatty liver disease
Alcohol-associated liver disease
Hemochromatosis
Viral hepatitis
Portal hypertension
Hirschsprung disease
Pyloric stenosis
Oral cancer
Benign liver tumors
Blood components
Coagulation (secondary hemostasis)
Clot retraction and fibrinolysis
Platelet plug formation (primary hemostasis)
Role of Vitamin K in coagulation
Iron deficiency anemia
Alpha-thalassemia
Beta-thalassemia
Anemia of chronic disease
Aplastic anemia
Autoimmune hemolytic anemia
Sickle cell disease (NORD)
Von Willebrand disease
Hemophilia
Acute leukemia
Chronic leukemia
Hodgkin lymphoma
Non-Hodgkin lymphoma
Polycythemia vera (NORD)
Essential thrombocythemia (NORD)
Skeletal system anatomy and physiology
Cartilage structure and growth
Bone remodeling and repair
Fibrous, cartilage, and synovial joints
Rheumatoid arthritis
Gout
Systemic lupus erythematosus
Raynaud phenomenon
Amyloidosis
Scleroderma
Fibromyalgia
Osteoarthritis
Paget disease of bone
Osteoporosis
Legg-Calve-Perthes disease
Osteomalacia and rickets
Osgood-Schlatter disease (traction apophysitis)
Septic arthritis
Osteomyelitis
Lordosis, kyphosis, and scoliosis
Rotator cuff tear
Meniscus tear
Sprained ankle
Compartment syndrome
Bone tumors
Developmental dysplasia of the hip
Nervous system anatomy and physiology
Anatomy and physiology of the eye
Anatomy and physiology of the ear
Neuron action potential
Sympathetic nervous system
Parasympathetic nervous system
Adrenergic receptors
Cholinergic receptors
Cerebellum
Optic pathways and visual fields
Brachial plexus
Seizures and epilepsy
Migraine
Tension headache
Cluster headache
Alzheimer disease
Frontotemporal dementia
Vascular dementia
Dementia with Lewy bodies
Multiple sclerosis
Muscular dystrophy
Bell palsy
Concussion and traumatic brain injury
Cauda equina syndrome
Neurogenic bladder
Parkinson disease
Sciatica
Carpal tunnel syndrome
Eustachian tube dysfunction
Glaucoma
Major depressive disorder
Major depressive disorder with seasonal pattern
Suicide
Bipolar and related disorders
Generalized anxiety disorder
Post-traumatic stress disorder
Schizophrenia
Alcohol use disorder
Tobacco use disorder
Cannabis use disorder
Opioid use disorder
Cocaine use disorder
Cluster A personality disorders
Cluster B personality disorders
Cluster C personality disorders
Autism spectrum disorder
Attention deficit hyperactivity disorder
Learning disability
Delirium
Renal system anatomy and physiology
Movement of water between body compartments
Renal clearance
Osmoregulation
Antidiuretic hormone
Regulation of renal blood flow
Glomerular filtration
Proximal convoluted tubule
Loop of Henle
Potassium homeostasis
Phosphate, calcium and magnesium homeostasis
Sodium homeostasis
The role of the kidney in acid-base balance
Diabetic nephropathy
Lower urinary tract infection
Acute pyelonephritis
Chronic pyelonephritis
Kidney stones
Urinary incontinence
Hydronephrosis
Polycystic kidney disease
Estrogen and progesterone
Menstrual cycle
Menopause
Oxytocin and prolactin
Pregnancy
Anatomy and physiology of the female reproductive system
Anatomy and physiology of the male reproductive system
Testosterone
Development of the reproductive system
Puberty and Tanner staging
Ovarian cyst
Endometriosis
Uterine fibroid
Endometritis
Amenorrhea
Benign prostatic hyperplasia
Pelvic inflammatory disease
Cervical cancer
Endometrial cancer
Breast cancer
Respiratory system anatomy and physiology
Respiratory syncytial virus
Pneumonia
Asthma
Chronic bronchitis
Emphysema
Nasal polyps
Sinusitis
Bacterial epiglottitis
Allergic rhinitis
Upper respiratory tract infection
Laryngitis
Retropharyngeal and peritonsillar abscesses
Pulmonary hypertension
Lung cancer
Mesothelioma
Sleep apnea
Restrictive lung diseases
Vitiligo

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Skeletal system anatomy and physiology

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We all have 206 bones, and together they make up the skeleton which gives the body structure, protects important organs like the brain and heart, and allows muscles to facilitate movement.

Without bones you’d be a shapeless, immobile blob.

Normally, the skeleton can be broken down into the axial and the appendicular skeleton.

The axial skeleton consists of bones located along the vertical axis of your body. It contains 80 bones; 22 bones that make up the skull, 33 vertebrae, 24 ribs, and the sternum.

The appendicular skeleton consists of bones in your limbs as well as the bones that attach the limb bones to the axial skeleton, like the pelvis and the scapulae.

The appendicular skeleton is made up of around 126 bones; 4 bones in both shoulders, 6 bones in the arms, 54 bones in the hands, 2 hip bones that form the pelvic girdle, 8 bones in the legs, and 52 bones in the feet.

Now there are 5 types of bones based on their shape - long bones, short bones, flat bones, sesamoid bones, and irregular bones.

Long bones are longer than they are wide, and they’re in the limbs and include the humerus, radius, and ulna in the arms; as well as the metacarpals and phalanges of the hand and fingers.

Long bones also include the femur, tibia, and fibula in the leg as well as metatarsals and phalanges of the feet and toes.

During childhood and adolescence, long bones continues to grow and are the bones that are responsible for your height.

Unlike long bones, the short bones have a similar length and width, and that gives them a round or cube-like appearance. They include the carpal bones of the wrist and tarsal bones of the ankle and their main functions are to support the hand and foot.

Flat bones are thin bones, and some of them are curved. They include bones of the skull, the two shoulder blades or scapulae, sternum, and ribs. Their main job is to serve as armor plating that protects vital organs like the brain, heart, and lungs.

Sesamoid bones, are embedded in tendons and they’re like giant sesame seeds - in shape. Most of these bones can be found in the metacarpal phalangeal joints in the hand and metatarsal phalangeal joints in the feet.

The larger sesamoid bones include the pisiform bone that’s in the wrist, and the patella which is the kneecap.

These bones increase the angle between the bone and the tendon of muscles which gives the muscles more leverage. The sesamoid bones also provide support and protects the tendon from wear and tear.

The last type of bones are the irregular bones which are basically the misfits that don’t fit into any of the previous categories. This includes the the facial bones, the mandible, the vertebrae of the vertebral column, and the sacrum and coccyx.

Now, some bones have surface structures that help them function. For example, bones can have tubercles which are small bumps on the bone that serve as an attachment site for muscles.

A large tubercle is called a tuberosity, and an example is the deltoid tuberosity on the humerus which is where the deltoid muscle attaches.

Holes in the bone that allow blood vessels or nerves to pass through are called foramen. An example of that is the foramen magnum in the occipital bone of the skull, which allows the spinal cord to exit the skull.

Bones can also have canals, which are tunnels within the bone that allow structures like blood vessels or nerves to travel through. An example is the optic canal in the sphenoid bone which allows the optic nerve, to travel from the brain to the eyes.

Another name for a canal is a meatus, like the external auditory meatus of the ear, located in the temporal bone which lets sound pass through to the eardrum.

Some bones have a fossa which is a depression within the bone, where another structure rests. One example is the hypophyseal fossa or sella turcica on the sphenoid bone which is like a tiny seat where the pituitary gland rests.

Also, there are sinuses and cavities, which are empty spaces within a bone or formed by multiple bones coming together. Examples include the nasal cavity which is formed by the maxilla, the nasal bone and palatine bone, as well as the paranasal sinuses, like the maxillary sinus, is located within the maxillary bone.

Key Takeaways

The skeletal system is made up of bones, cartilage, and other connective tissues that provide support and structure to the body. The primary functions of the skeletal system are to protect internal organs, provide support for the body, allow for movement, produce blood cells, and store minerals such as calcium and phosphorus.

Bones are living tissues that are constantly undergoing remodeling, a process in which old bone tissue is broken down and new bone tissue is formed. Bone tissue is composed of cells called osteoblasts, osteocytes, and osteoclasts, as well as a matrix of collagen and mineral salts such as calcium and phosphorus.

Cartilage is a type of connective tissue that provides cushioning and support to joints. It is composed of cells called chondrocytes and a matrix of collagen and proteoglycans. Other connective tissues include ligaments and tendons, which help to connect bones to other bones and muscles, respectively.

Sources

  1. "Medical Physiology" Elsevier (2016)
  2. "Physiology" Elsevier (2017)
  3. "Human Anatomy & Physiology" Pearson (2018)
  4. "Principles of Anatomy and Physiology" Wiley (2014)
  5. "On estimating the directionality distribution in pedicle trabecular bone from micro-CT images" Physiological Measurement (2014)
  6. "Crisóstomo Martínez, 1638-1694 <e1>The Discoverer of Trabecular Bone" Endocrine (2002)
  7. "Regulation of cortical and trabecular bone mass by communication between osteoblasts, osteocytes and osteoclasts" Archives of Biochemistry and Biophysics (2014)
  8. "Normal bone anatomy and physiology" Clin J Am Soc Nephrol (2008)