Reviewed by Rishi Desai, MD, MPH
Ulcerative colitis is a form of inflammatory bowel disease that causes inflammation and ulcers in the colon. The inflammation extends to the mucosa and submucosa only. The main symptom of active disease is diarrhea mixed with blood. The treatment of ulcerative colitis consists of 5-aminosalicylic preparations (eg, mesalamine), 6-mercaptopurine, infliximab, however, the only permanent solution is colectomy.